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To better understand the dopaminergic defects that give rise to dystonia, Rose et al. generate a knockin mouse model that recapitulates the core features of the human disorder.
Although seizures reflect excessive excitation, the nature of interictal spikes is unclear. Muldoon et al. show that GABAergic neurons are the main participants in such spikes in a mouse model of epilepsy.
In an ECG study of 52 cases, Jaffer et al. reveal dynamic cardiac repolarisation or conduction abnormalities in more than half of those tested.

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2014 Impact Factor: 9.196

We are celebrating the announcement of the latest Impact Factor with a collection of the ten most cited articles from 2013 - 2015 freely available online.

100-Year Anniversary of Sir William Richard Gowers

This article collection celebrates the work of Sir William Gowers (1845 - 1915) on the 100-year anniversary of his death with a selection of articles both written by him, and about him.
Sir William Gowers was described by Macdonald Critchley as 'probably the greatest neurologist of all time'. He lived in England in the late 19th century, and during his illustrious career was responsible for discovering the first removable spine tumour, inventing the patella hammer, and writing the two-volume Manual of Diseases of the Nervous System (1886, 1888), which is still used today.

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Key Figures in Neurology - 100-year Anniversary Collection

This year marks the 100-year anniversary of the deaths of two of the most well renowned figures in neurology, Henry Charlton Bastian (1837 - 1915) and Aloysius "Alois" Alzheimer (1864 - 1915). This collection brings together articles published in Brain, both by and about them, free to access online until the 30th of November.

Bastian was an important pioneer of neurology, discovering the anterior spinocerebellar tract of the spinal cord, and showing that a complete cut on the upper spinal cord removes reflexes and muscular tone below the lesion. 


Alzheimer is primarily known for the discovery of the disease that was later named after him by Emil Kraepelin. Alzheimer identified the 'unusual disease of the cerebral cortex' in 51-year-old patient Auguste Deter, who presented with memory loss, disorientation, and many other symptoms that are now associated with Alzheimer's disease.

Brain on the OUP blog

Deborah Thorpe and Jane Alty discuss the potential neurological disorders that could have affected the medieval writer known as the 'Tremulous Hand of Worcester'.
Tamar Makin explains how the brain reacts to losing a limb, the cause of the pain, and potential ways of treating it.
Robert Turner and Jörn-Henrik Jacobsen discuss the relationship between Alzheimer's Disease and music
Laura McWhirter and Jon Stone talk about the impact of electrotherapy on neurological symptoms.
Caroline Skirrow and Torsten Baldeweg discuss the effect of brain surgery on children with epilepsy.

Free editorials

The editorial from each issue of Brain is freely available to read online.

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The latest Alzheimer's Disease research

Take a look at our collection of articles made up of the latest, cutting-edge research on Alzheimer's Disease published in Brain.

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