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Jones et al. present an in-depth analysis of changes within these subsystems and relate them to biomarker profiles across the Alzheimer’s disease spectrum. Results support a cascading network failure model of Alzheimer’s disease.
 
 
 
Rapp et al. analyse the lesion distribution of 33 individuals with deficits affecting either or both memory processes.
 
 
Falsini et al. show that nerve growth factor (NGF) eye drops are well-tolerated and produce improvements in electrophysiological parameters compared to placebo.
 

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2014 Impact Factor: 9.196

 
We are celebrating the announcement of the latest Impact Factor with a collection of the ten most cited articles from 2013 - 2015 freely available online.

100-Year Anniversary of Sir William Richard Gowers

This article collection celebrates the work of Sir William Gowers (1845 - 1915) on the 100-year anniversary of his death with a selection of articles both written by him, and about him.
 
Sir William Gowers was described by Macdonald Critchley as 'probably the greatest neurologist of all time'. He lived in England in the late 19th century, and during his illustrious career was responsible for discovering the first removable spine tumour, inventing the patella hammer, and writing the two-volume Manual of Diseases of the Nervous System (1886, 1888), which is still used today.

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Key Figures in Neurology - 100-year Anniversary Collection

This year marks the 100-year anniversary of the deaths of two of the most well renowned figures in neurology, Henry Charlton Bastian (1837 - 1915) and Aloysius "Alois" Alzheimer (1864 - 1915). This collection brings together articles published in Brain, both by and about them, free to access online until the 30th of November.

Bastian was an important pioneer of neurology, discovering the anterior spinocerebellar tract of the spinal cord, and showing that a complete cut on the upper spinal cord removes reflexes and muscular tone below the lesion. 

 

Alzheimer is primarily known for the discovery of the disease that was later named after him by Emil Kraepelin. Alzheimer identified the 'unusual disease of the cerebral cortex' in 51-year-old patient Auguste Deter, who presented with memory loss, disorientation, and many other symptoms that are now associated with Alzheimer's disease.

Brain on the OUP blog

 
Erin Golden and Keith A. Josephs discuss musical hallucinations and their relationship to neurological disease on the OUP blog, based on their article 'Minds on replay: musical hallucinations and their relationship to neurological disease'.
 

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