COMPUTERIZED TOMOGRAPHY OF THE BRAIN IN CHRONIC ALCOHOLISM: A SURVEY AND FOLLOW-UP STUDY

doi:10.1093/brain/105.3.497

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Brain, Vol. 105, No. 3, 497-514, 1982
© 1982 Guarantors of Brain
doi: 10.1093/brain/105.3.497

COMPUTERIZED TOMOGRAPHY OF THE BRAIN IN CHRONIC ALCOHOLISM

A SURVEY AND FOLLOW-UP STUDY

M. A. RON, W. ACKER, G. K. SHAW and W. A. LISHMAN

From the Institute of Psychiatry, De Crespigny Park, London SE5 8AF and Bexley Hospital, Bexley, Kent

One hundred male alcoholics from an inpatient treatment unitwere examined by computerized axial tomography. All were withoutclinically overt signs of brain damage. Fifty age-matched normalvolunteers were used for comparison. Radiological indices differedmarkedly between the two groups, reflecting a high incidenceof cortical shrinkage and ventricular dilatation among the alcoholics.Clinicoradiological correlations are discussed and the resultsof follow-up with rescanning are reported. Abstinence appearedto be strongly related to slow partial resolution of the CTscan changes.

Received January 18, 1982.
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