Brain, Vol. 106, No. 4, 981-1000, 1983
© 1983 Guarantors of Brain
research-article |
STEREOTAXIC THALAMOTOMY IN 55 CASES OF DYSTONIA
Reta Lila Weston Institute of Neurological Studies, The Middlesex Hospital Medical School London WIN 8AA
The results of stereotaxic thalamotomy in 55 cases of dystonia are presented. The 16 cases with generalized dystonia were of varied pathogenesis, only 7 being typical of the idiopathic form of adolescent onset. Four of the 16 cases benefited considerably, but the others showed little or no lasting improvement. These results are in contrast to those obtained by Cooper (1976).
Of the 27 cases with segmental or focal dystonia, 22 had spasmodic torticollis; 16 of these had bilateral thalamotomies, and 62 per cent were much improved. The incidence of operative complications, in particular dysarthria, was high following bilateral lesions.
The incidence of hemiparesis, known to have persisted for more than a year, was 15 per cent. This complication was as frequent in those with unilateral as with bilateral thalamotomies. The incidence of dysarthria in those without preoperative bulbar dystonia was much higher in those who had bilateral lesions (56 per cent) as compared with those who had unilateral lesions (11 per cent).
The group that has been identified as benefiting greatly from stereotaxic surgery comprises those with hemidystonia following unilateral brain damage. In these patients, symptomatic improvement in abnormal movement is striking and the incidence of operative side effects from unilateral lesions is low.
Received October 27, 1982.
Revised March 31, 1983.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M. Vidailhet, L. Vercueil, J.-L. Houeto, P. Krystkowiak, A.-L. Benabid, P. Cornu, C. Lagrange, S. Tezenas du Montcel, D. Dormont, S. Grand, et al. Bilateral Deep-Brain Stimulation of the Globus Pallidus in Primary Generalized Dystonia N. Engl. J. Med., February 3, 2005; 352(5): 459 - 467. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Detante, L. Vercueil, S. Thobois, E. Broussolle, N. Costes, F. Lavenne, S. Chabardes, D. Lebars, M. Vidailhet, A.-L. Benabid, et al. Globus pallidus internus stimulation in primary generalized dystonia: a H215O PET study Brain, August 1, 2004; 127(8): 1899 - 1908. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. L. Albright Neurosurgical Treatment of Spasticity and Other Pediatric Movement Disorders J Child Neurol, January 1, 2003; 18(1_suppl): S67 - S78. [Abstract] [PDF]
|
|
|
|
 |
|
 J K Krauss, T Pohle, R Weigel, and J-M Burgunder Deep brain stimulation of the centre median-parafascicular complex in patients with movement disorders J. Neurol. Neurosurg. Psychiatry, April 1, 2002; 72(4): 546 - 548. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C Chuang, S Fahn, and S J Frucht The natural history and treatment of acquired hemidystonia: report of 33 cases and review of the literature J. Neurol. Neurosurg. Psychiatry, January 1, 2002; 72(1): 59 - 67. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. A. Lenz and N. N. Byl Reorganization in the Cutaneous Core of the Human Thalamic Principal Somatic Sensory Nucleus (Ventral Caudal) in Patients With Dystonia J Neurophysiol, December 1, 1999; 82(6): 3204 - 3212. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. A. Lenz, C. J. Jaeger, M. S. Seike, Y. C. Lin, S. G. Reich, M. R. DeLong, and J. L. Vitek Thalamic Single Neuron Activity in Patients With Dystonia: Dystonia-Related Activity and Somatic Sensory Reorganization J Neurophysiol, November 1, 1999; 82(5): 2372 - 2392. [Abstract] [Full Text] [PDF]
|
|