Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (24)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by PIERROT-DESEILLIGNY, CH.
Right arrow Articles by GOASGUEN, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by PIERROT-DESEILLIGNY, CH.
Right arrow Articles by GOASGUEN, J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Brain, Vol. 107, No. 4, 1019-1032, 1984
© 1984 Guarantors of Brain

research-article

ISOLATED ABDUCENS NUCLEUS DAMAGE DUE TO HISTIOCYTOSIS X

ELECTRO-OCULOGRAPHIC ANALYSIS AND PHYSIOLOGICAL DEDUCTIONS

CH. PIERROT-DESEILLIGNY and J. GOASGUEN

Unité de Recherches INSERM U 84, Hôpital de la Salpêtrière, Paris, and the Clinique de Neurologie. Hôpital d'Instruction des Armées du Val-de-grâce Paris

A case of complete rightward conjugate gaze paralysis, with electro-oculographic recordings, is reported. The only additional feature on clinical examination was a right infranuclear facial paresis. Radiographs of the chest showed multiple infiltrates in both lung fields; lung biopsy with ultrastructural study led to the diagnosis of histiocytosis X. ACT scan showed a single small tumourlike lesion, hyperdense and clearly defined, lying centrally in the fourth ventricle with a small ventral extension locared just to the right of the midline. With appropriate treatment all the clinical signs rapidly subsided, together with the disappearance of the right ventral extension of the lesion visible on the CT scan.

The clinical and CT scan data suggested that the initial parenchymatous damage almost exclusively involved the right abducens nucleus, a structure which is very rarely affected in an isolated manner. Both main clinical features of the abducens nucleus syndrome which distiguish it from the recently described paramedian pontine reticular formation syndrome were present, namely absence of all ipsilareral conjugate movements and persistence of ipsilaterally directed saocades in the contralateral hemifield of movement. Furthermore, differences between peak velocities of both eyes in oculocephalic movements suggested that a pathway analogous, at least functionally, to the ascending tract of Deiters described in the car and in the monkey may exist in man. Lastly, some recent clinical data concerning this unusual cause of CNS damage are briefly reviewed.

Received January 26, 1984. Revised April 3, 1984.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Neurol. Neurosurg. PsychiatryHome page
D Milea, M Napolitano, H Dechy, P Le Hoang, J-Y Delattre, and C Pierrot-Deseilligny
Complete bilateral horizontal gaze paralysis disclosing multiple sclerosis
J. Neurol. Neurosurg. Psychiatry, February 1, 2001; 70(2): 252 - 255.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
F. Thömke and H. C. Hopf
Pontine lesions mimicking acute peripheral vestibulopathy
J. Neurol. Neurosurg. Psychiatry, March 1, 1999; 66(3): 340 - 349.
[Abstract] [Full Text]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.