Brain, Vol. 111, No. 3, 553-576, 1988
© 1988 Guarantors of Brain
research-article |
PROCESSING OF SEMANTIC ANOMALY BY RIGHT AND LEFT HEMISPHERES OF COMMISSUROTOMY PATIENTS
EVIDENCE FROM EVENT-RELATED BRAIN POTENTIALS
From the Department of Neurosciences, University of California San Diego, California Division of Cognitive Neuroscience, Department of Neurology, Cornell Medical Center New York, USA
Correspondence to:
Correspondence to: Dr Marta Kutas, Department of Neurosciences, M-008, University of California, San Diego, California 92093, USA.
The ability of 5 commissurotomized patients to appreciate semantic anomalies presented to their right and left hemispheres was tested using both electrophysiological and behavioural measures. In all cases, the patients heard sentence fragments that were completed either by semantically congruous or incongruous words briefly flashed to the left visual field, right visual field or to both fields simultaneously. A dissociation between behavioural and event-related brain potential (ERP) measures was observed. All 5 patients were able to indicate by a pointing response with greater than chance accuracy whether the terminal word of a sentence made sense (i.e., appropriate for the context) or was nonsensical. This was true regardless of the hemisphere receiving the terminal word. Likewise, all the patients responded to right visual field anomalies with a cerebral potential (N400) that was typically elicited by such words in control subjects. In contrast, only those 2 patients who developed an overt speech capability under the control of the right hemisphere produced N400 waves in response to left visual field anomalies. These findings were interpreted as suggesting possible relationships within language generation and semantic priming.
Received April 23, 1987. Revised August 25, 1987. Accepted September 25, 1987.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M. S. Gazzaniga Cerebral specialization and interhemispheric communication: Does the corpus callosum enable the human condition? Brain, July 1, 2000; 123(7): 1293 - 1326. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Cao, E. M. Vikingstad, K. P. George, A. F. Johnson, and K. M. A. Welch Cortical Language Activation in Stroke Patients Recovering From Aphasia With Functional MRI Stroke, November 1, 1999; 30(11): 2331 - 2340. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Gazzaniga Organization of the human brain Science, September 1, 1989; 245(4921): 947 - 952. [Abstract] [PDF]
|
|
|
|
 |
|
 S. Bentin Electrophysiological Studies of Visual Word Perception, Lexical Organization, and Semantic Processing: A Tutorial Review Language and Speech, July 1, 1989; 32(3): 205 - 220. [Abstract] [PDF]
|
|