Brain, Vol. 113, No. 5, 1383-1393, 1990
© 1990 Guarantors of Brain
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THE COMPORTMENTAL LEARNING DISABILITIES OF EARLY FRONTAL LOBE DAMAGE
Bullard and Denny-Brown Laboratories, the Division of Behavioral Neurology and Neuroscience of the Harvard Neurology Department and the Charles A. Dana Research Institute of the Beth Israel Hospital Boston, USA
Correspondence to:
Correspondence to: Dr Bruce H. Price, Neurological Unit, Beth Israel Hospital, 330 Brookline Avenue, Boston. MA 02215, USA.
Two adult patients are described who suffered bilateral prefrontal damage early in life and who subsequently came to psychiatric attention because of severely aberrant behaviour. A battery of developmental psychology paradigms (not previously used to assess neurologically impaired individuals) showed that social and moral development of these 2 patients was arrested at an immature stage. In comparison with other types of brain damage which disrupt cognitive development, frontal damage acquired early in life appears to provide the neurological substrate for a special type of learning disability in the realms of insight, foresight, social judgement, empathy, and complex reasoning.
Received March 15, 1989. Revised August 1, 1989. Accepted October 18, 1989.
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