Brain, Vol. 115, No. 4, 1045-1059, 1992
© 1992 Guarantors of Brain
research-article |
EFFECTS OF FOCAL TRANSCRANIAL MAGNETIC STIMULATION ON SIMPLE REACTION TIME TO ACOUSTIC, VISUAL AND SOMATOSENSORY STIMULI
Human Cortical Physiology Unit, Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health Bethesda, Maryland, USA
Correspondence to:
Correspondence to. Dr Mark Hallett, Building 10, Room 5N226, NINDS, NIH, Bethesda, MD 20892, USA.
In a simple reaction time (RT) paradigm, magnetic stimulation of different intensities was delivered over different scalp positions and at variable delays before (negative) or after (positive) the go-signal. Magnetic stimulation shortened RT to different go-signals (auditory, visual and somatosensory stimuli) by approximately 30 ms when delivered over the motor cortex contralateral to the responding arm at intensities below motor threshold. This effect was maximal at a delay of approximately + 10 ms. A similar effect was found with suprathreshold stimulation to the ipsilateral motor cortex. Magnetic stimulation over other scalp areas did not affect RT regardless of the delay. No differences were found between the effects on elbow flexion and thumb abduction. The shortening of RT was not associated with changes in the timing development of premovement excitability increase in the motor cortex. We conclude that magnetic stimulation shortens RT by inducing an earlier initiation of this excitability increase
Received January 2, 1992. Accepted March 30, 1992.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  S. A. Coombes, C. Tandonnet, H. Fujiyama, C. M. Janelle, J. H. Cauraugh, and J. J. Summers Emotion and motor preparation: A transcranial magnetic stimulation study of corticospinal motor tract excitability Cogn Affect Behav Neurosci, December 1, 2009; 9(4): 380 - 388. [Abstract] [PDF]
|
|
|
|
 |
|
 W. J. Z\#8217;Graggen, A. B. Conforto, R. Wiest, L. Remonda, C. W. Hess, and A. Kaelin-Lang Mapping of direction and muscle representation in the human primary motor cortex controlling thumb movements J. Physiol., May 1, 2009; 587(9): 1977 - 1987. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Bosco, M. Carrozzo, and F. Lacquaniti Contributions of the Human Temporoparietal Junction and MT/V5+ to the Timing of Interception Revealed by Transcranial Magnetic Stimulation J. Neurosci., November 12, 2008; 28(46): 12071 - 12084. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. A. Fridman, T. Hanakawa, M. Chung, F. Hummel, R. C. Leiguarda, and L. G. Cohen Reorganization of the human ipsilesional premotor cortex after stroke Brain, April 1, 2004; 127(4): 747 - 758. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. J. Moser, R. E. Jorge, F. Manes, S. Paradiso, M. L. Benjamin, and R. G. Robinson Improved executive functioning following repetitive transcranial magnetic stimulation Neurology, April 23, 2002; 58(8): 1288 - 1290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. D MacKinnon and J. C Rothwell Time-varying changes in corticospinal excitability accompanying the triphasic EMG pattern in humans J. Physiol., November 1, 2000; 528(3): 633 - 645. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Leocani, L. G. Cohen, E. M. Wassermann, K. Ikoma, and M. Hallett Human corticospinal excitability evaluated with transcranial magnetic stimulation during different reaction time paradigms Brain, June 1, 2000; 123(6): 1161 - 1173. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Topka, S. Mescheriakov, A. Boose, R. Kuntz, I. Hertrich, L. Seydel, J. Dichgans, and J. Rothwell A cerebellar-like terminal and postural tremor induced in normal man by transcranial magnetic stimulation Brain, August 1, 1999; 122(8): 1551 - 1562. [Abstract] [Full Text] [PDF]
|
|