Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (769)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by HODGES, J. R.
Right arrow Articles by FUNNELL, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by HODGES, J. R.
Right arrow Articles by FUNNELL, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Brain, Vol. 115, No. 6, 1783-1806, 1992
© 1992 Guarantors of Brain

research-article

SEMANTIC DEMENTIA

PROGRESSIVE FLUENT APHASIA WITH TEMPORAL LOBE ATROPHY

JOHN R. HODGES1, KARALYN PATTERSON2, SUSAN OXBURY3 and ELAINE FUNNELL4

1University of Cambridge Clinical School, Addenbrooke's Hospital London, UK 2MRC Applied Psychology Unit, Cambridge London, UK 3Department of Neuropsychology, Radcliffe Infirmary, Oxford London, UK 4Department of Psychology, Royal Holloway College, University of London London, UK

Correspondence to: Correspondence to: Dr J. R. Hodges, Department of Neurology, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK.

We report five patients with a stereotyped clinical syndrome characterized by fluent dysphasia with severe anomia, reduced vocabulary and promment impairment of single-word comprehension, progressing to a stage of virtually complete dissolution of the semantic components of language. A marked reduction in the ability to generate exemplars from restricted semantic categories (e.g. animals, vehicles, etc.) was a consistent and early feature. Tests of semantic memory demonstrated a radically impoverished knowledge about a range of living and man-made items. In contrast, phonology and grammar of spoken language were largely preserved, as was comprehension of complex syntactic commands. Reading showed a pattern of surface dyslexia. Autobiographical and day-to-day (episodic) memory were relatively retained. Non-verbal memory, perceptual and visuospatial abilities were also strikingly preserved. In some cases, behavioural and personality changes may supervene; one patient developed features of the Kluver-Bucy Syndrome. Radiological investigations have shown marked focal temporal atrophy in all five patients, and functional imaging by single positron emission tomography and positron emission tomography (one case) have implicated the dominant temporal lobe in all five. In the older literature, such cases would have been subsumed under the rubric of Pick's disease. Others have been included in series with progressive aphasia. We propose the term semantic dementia, first coined by Snowden et al. (1989), to designate this clinical syndrome.

Received April 6, 1992. Accepted May 13, 1992.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Cereb CortexHome page
J. R. Binder, R. H. Desai, W. W. Graves, and L. L. Conant
Where Is the Semantic System? A Critical Review and Meta-Analysis of 120 Functional Neuroimaging Studies
Cereb Cortex, December 1, 2009; 19(12): 2767 - 2796.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
E. A. Race, D. Badre, and A. D. Wagner
Multiple Forms of Learning Yield Temporally Distinct Electrophysiological Repetition Effects
Cereb Cortex, November 13, 2009; (2009) bhp233v1.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. E. Warren, J. T. Crinion, M. A. Lambon Ralph, and R. J. S. Wise
Anterior temporal lobe connectivity correlates with functional outcome after aphasic stroke
Brain, November 10, 2009; (2009) awp270v1.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. Grogan, D. W. Green, N. Ali, J. T. Crinion, and C. J. Price
Structural Correlates of Semantic and Phonemic Fluency Ability in First and Second Languages
Cereb Cortex, November 1, 2009; 19(11): 2690 - 2698.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. R. Hodges, J. Mitchell, K. Dawson, M. G. Spillantini, J. H. Xuereb, P. McMonagle, P. J. Nestor, and K. Patterson
Semantic dementia: demography, familial factors and survival in a consecutive series of 100 cases
Brain, October 5, 2009; (2009) awp248v1.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. A. Knibb, A. M. Woollams, J. R. Hodges, and K. Patterson
Making sense of progressive non-fluent aphasia: an analysis of conversational speech
Brain, October 1, 2009; 132(10): 2734 - 2746.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
F. Agosta, R. G. Henry, R. Migliaccio, J. Neuhaus, B. L. Miller, N. F. Dronkers, S. M. Brambati, M. Filippi, J. M. Ogar, S. M. Wilson, et al.
Language networks in semantic dementia
Brain, September 16, 2009; (2009) awp233v1.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
K. Rascovsky, M. E. Growdon, I. R. Pardo, S. Grossman, and B. L. Miller
'The quicksand of forgetfulness': semantic dementia in One Hundred Years of Solitude
Brain, September 1, 2009; 132(9): 2609 - 2616.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
F. Corbett, E. Jefferies, S. Ehsan, and M. A. Lambon Ralph
Different impairments of semantic cognition in semantic dementia and semantic aphasia: evidence from the non-verbal domain
Brain, September 1, 2009; 132(9): 2593 - 2608.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. G. Ramayya, M. F. Glasser, and J. K. Rilling
A DTI Investigation of Neural Substrates Supporting Tool Use
Cereb Cortex, July 16, 2009; (2009) bhp141v1.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
M. A. Lambon Ralph, G. Pobric, and E. Jefferies
Conceptual Knowledge Is Underpinned by the Temporal Pole Bilaterally: Convergent Evidence from rTMS
Cereb Cortex, April 1, 2009; 19(4): 832 - 838.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
M. M. Saling
Verbal memory in mesial temporal lobe epilepsy: beyond material specificity
Brain, March 1, 2009; 132(3): 570 - 582.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
S. M. Wilson, S. M. Brambati, R. G. Henry, D. A. Handwerker, F. Agosta, B. L. Miller, D. P. Wilkins, J. M. Ogar, and M. L. Gorno-Tempini
The neural basis of surface dyslexia in semantic dementia
Brain, January 1, 2009; 132(1): 71 - 86.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
F. Campanella, M. Mondani, M. Skrap, and T. Shallice
Semantic access dysphasia resulting from left temporal lobe tumours
Brain, January 1, 2009; 132(1): 87 - 102.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
K. Czarnecki, J. R. Duffy, C. R. Nehl, S. A. Cross, J. R. Molano, C. R. Jack Jr, M. M. Shiung, K. A. Josephs, and B. F. Boeve
Very Early Semantic Dementia With Progressive Temporal Lobe Atrophy: An 8-Year Longitudinal Study
Arch Neurol, December 1, 2008; 65(12): 1659 - 1663.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
K. A. Josephs, J. L. Whitwell, P. Vemuri, M. L. Senjem, B. F. Boeve, D. S. Knopman, G. E. Smith, R. J. Ivnik, R. C. Petersen, and C. R. Jack Jr
The anatomic correlate of prosopagnosia in semantic dementia
Neurology, November 11, 2008; 71(20): 1628 - 1633.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
J. D. Rohrer, E. McNaught, J. Foster, S. L. Clegg, J. Barnes, R. Omar, E. K. Warrington, M. N. Rossor, J. D. Warren, and N. C. Fox
Tracking progression in frontotemporal lobar degeneration: Serial MRI in semantic dementia
Neurology, October 28, 2008; 71(18): 1445 - 1451.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Y. Y. Choi, N. A. Shamosh, S. H. Cho, C. G. DeYoung, M. J. Lee, J.-M. Lee, S. I. Kim, Z.-H. Cho, K. Kim, J. R. Gray, et al.
Multiple Bases of Human Intelligence Revealed by Cortical Thickness and Neural Activation
J. Neurosci., October 8, 2008; 28(41): 10323 - 10329.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
I. Kahn, J. R. Andrews-Hanna, J. L. Vincent, A. Z. Snyder, and R. L. Buckner
Distinct Cortical Anatomy Linked to Subregions of the Medial Temporal Lobe Revealed by Intrinsic Functional Connectivity
J Neurophysiol, July 1, 2008; 100(1): 129 - 139.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. D. Rohrer, W. D. Knight, J. E. Warren, N. C. Fox, M. N. Rossor, and J. D. Warren
Word-finding difficulty: a clinical analysis of the progressive aphasias
Brain, January 1, 2008; 131(1): 8 - 38.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
G. Pobric, E. Jefferies, and M. A. L. Ralph
Anterior temporal lobes mediate semantic representation: Mimicking semantic dementia by using rTMS in normal participants
PNAS, December 11, 2007; 104(50): 20137 - 20141.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
L. L. Chao, N. Schuff, E. M. Clevenger, S. G. Mueller, H. J. Rosen, M. L. Gorno-Tempini, J. H. Kramer, B. L. Miller, and M. W. Weiner
Patterns of White Matter Atrophy in Frontotemporal Lobar Degeneration
Arch Neurol, November 1, 2007; 64(11): 1619 - 1624.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Awad, J. E. Warren, S. K. Scott, F. E. Turkheimer, and R. J. S. Wise
A Common System for the Comprehension and Production of Narrative Speech
J. Neurosci., October 24, 2007; 27(43): 11455 - 11464.
[Abstract] [Full Text] [PDF]

Home page
 J Geriatr Psychiatry NeurolHome page
J. Medina and S. Weintraub
Depression in Primary Progressive Aphasia
J Geriatr Psychiatry Neurol, September 1, 2007; 20(3): 153 - 160.
[Abstract] [PDF]

Home page
 BrainHome page
N. Nelissen, M. Vandenbulcke, K. Fannes, A. Verbruggen, R. Peeters, P. Dupont, K. Van Laere, G. Bormans, and R. Vandenberghe
A{beta} amyloid deposition in the language system and how the brain responds
Brain, August 1, 2007; 130(8): 2055 - 2069.
[Abstract] [Full Text] [PDF]

Home page
 J. Neuropsychiatry Clin. Neurosi.Home page
M. F. Mendez
Impaired Knowledge for Fruits and Vegetables in Semantic Dementia
J Neuropsychiatry Clin Neurosci, August 1, 2007; 19(3): 349 - 350.
[Full Text] [PDF]

Home page
 BrainHome page
C. H. Williams-Gray, T. Foltynie, C. E. G. Brayne, T. W. Robbins, and R. A. Barker
Evolution of cognitive dysfunction in an incident Parkinson's disease cohort
Brain, July 1, 2007; 130(7): 1787 - 1798.
[Abstract] [Full Text] [PDF]

Home page
 Phil Trans R Soc BHome page
K. Patterson
The reign of typicality in semantic memory
Phil Trans R Soc B, May 29, 2007; 362(1481): 813 - 821.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
M. A. Lambon Ralph, C. Lowe, and T. T. Rogers
Neural basis of category-specific semantic deficits for living things: evidence from semantic dementia, HSVE and a neural network model
Brain, April 1, 2007; 130(4): 1127 - 1137.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
Y Nishio, H Kazui, M Hashimoto, K Shimizu, K Onouchi, S Mochio, K Suzuki, and E Mori
Actions anchored by concepts: defective action comprehension in semantic dementia
J. Neurol. Neurosurg. Psychiatry, December 1, 2006; 77(12): 1313 - 1317.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. R. Hodges
Alzheimer's centennial legacy: origins, landmarks and the current status of knowledge concerning cognitive aspects.
Brain, November 1, 2006; 129(Pt 11): 2811 - 2822.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
I. L. Ber, E. Guedj, A. Gabelle, P. Verpillat, M. Volteau, C. Thomas-Anterion, M. Decousus, D. Hannequin, P. Vera, L. Lacomblez, et al.
Demographic, neurological and behavioural characteristics and brain perfusion SPECT in frontal variant of frontotemporal dementia.
Brain, November 1, 2006; 129(Pt 11): 3051 - 3065.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
A.-L. R. Adlam, K. Patterson, T. T. Rogers, P. J. Nestor, C. H. Salmond, J. Acosta-Cabronero, and J. R. Hodges
Semantic dementia and fluent primary progressive aphasia: two sides of the same coin?
Brain, November 1, 2006; 129(Pt 11): 3066 - 3080.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
R. R. Davies, C. M. Kipps, J. Mitchell, J. J. Kril, G. M. Halliday, and J. R. Hodges
Progression in Frontotemporal Dementia: Identifying a Benign Behavioral Variant by Magnetic Resonance Imaging
Arch Neurol, November 1, 2006; 63(11): 1627 - 1631.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. S. Snowden, S. M. Pickering-Brown, I. R. Mackenzie, A. M. T. Richardson, A. Varma, D. Neary, and D. M. A. Mann
Progranulin gene mutations associated with frontotemporal dementia and progressive non-fluent aphasia
Brain, November 1, 2006; 129(11): 3091 - 3102.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
P. McMonagle, M. Blair, and A. Kertesz
Corticobasal degeneration and progressive aphasia
Neurology, October 24, 2006; 67(8): 1444 - 1451.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
J. T. Crinion, E. A. Warburton, M. A. Lambon-Ralph, D. Howard, and R. J.S. Wise
Listening to Narrative Speech after Aphasic Stroke: the Role of the Left Anterior Temporal Lobe
Cereb Cortex, August 1, 2006; 16(8): 1116 - 1125.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
E. Jefferies and M. A. Lambon Ralph
Semantic impairment in stroke aphasia versus semantic dementia: a case-series comparison
Brain, August 1, 2006; 129(8): 2132 - 2147.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
G. Spitsyna, J. E. Warren, S. K. Scott, F. E. Turkheimer, and R. J. S. Wise
Converging language streams in the human temporal lobe.
J. Neurosci., July 12, 2006; 26(28): 7328 - 7336.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
B. T. Gold, D. A. Balota, S. J. Jones, D. K. Powell, C. D. Smith, and A. H. Andersen
Dissociation of automatic and strategic lexical-semantics: functional magnetic resonance imaging evidence for differing roles of multiple frontotemporal regions.
J. Neurosci., June 14, 2006; 26(24): 6523 - 6532.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
K. A. Josephs, J. R. Duffy, E. A. Strand, J. L. Whitwell, K. F. Layton, J. E. Parisi, M. F. Hauser, R. J. Witte, B. F. Boeve, D. S. Knopman, et al.
Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech
Brain, June 1, 2006; 129(6): 1385 - 1398.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. C. H. Lee, M. J. Buckley, D. Gaffan, T. Emery, J. R. Hodges, and K. S. Graham
Differentiating the roles of the hippocampus and perirhinal cortex in processes beyond long-term declarative memory: a double dissociation in dementia.
J. Neurosci., May 10, 2006; 26(19): 5198 - 5203.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
P. Garrard and E. Carroll
Lost in semantic space: a multi-modal, non-verbal assessment of feature knowledge in semantic dementia
Brain, May 1, 2006; 129(5): 1152 - 1163.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
S. Konishi, T. Asari, K. Jimura, J. Chikazoe, and Y. Miyashita
Activation Shift from Medial to Lateral Temporal Cortex Associated with Recency Judgements Following Impoverished Encoding
Cereb Cortex, April 1, 2006; 16(4): 469 - 474.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
H.E. Moss, S. Abdallah, P. Fletcher, P. Bright, L. Pilgrim, K. Acres, and L.K. Tyler
Selecting Among Competing Alternatives: Selection and Retrieval in the Left Inferior Frontal Gyrus
Cereb Cortex, November 1, 2005; 15(11): 1723 - 1735.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
E. Le Rhun, F. Richard, and F. Pasquier
Natural history of primary progressive aphasia
Neurology, September 27, 2005; 65(6): 887 - 891.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
A. M. Lipton, K. A. Ohman, K. B. Womack, L. S. Hynan, E. T. Ninman, and L. H. Lacritz
Subscores of the FAB differentiate frontotemporal lobar degeneration from AD
Neurology, September 13, 2005; 65(5): 726 - 731.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
B. T. Gold, D. A. Balota, B. A. Kirchhoff, and R. L. Buckner
Common and Dissociable Activation Patterns Associated with Controlled Semantic and Phonological Processing: Evidence from fMRI Adaptation
Cereb Cortex, September 1, 2005; 15(9): 1438 - 1450.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
R. R. Davies, J. R. Hodges, J. J. Kril, K. Patterson, G. M. Halliday, and J. H. Xuereb
The pathological basis of semantic dementia
Brain, September 1, 2005; 128(9): 1984 - 1995.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
J. M. Rodd, M. H. Davis, and I. S. Johnsrude
The Neural Mechanisms of Speech Comprehension: fMRI studies of Semantic Ambiguity
Cereb Cortex, August 1, 2005; 15(8): 1261 - 1269.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M Grossman and P Moore
A longitudinal study of sentence comprehension difficulty in primary progressive aphasia
J. Neurol. Neurosurg. Psychiatry, May 1, 2005; 76(5): 644 - 649.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
H.E. Moss, J.M. Rodd, E.A. Stamatakis, P. Bright, and L.K. Tyler
Anteromedial Temporal Cortex Supports Fine-grained Differentiation among Objects
Cereb Cortex, May 1, 2005; 15(5): 616 - 627.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
W. W. Seeley, A. M. Bauer, B. L. Miller, M. L. Gorno-Tempini, J. H. Kramer, M. Weiner, and H. J. Rosen
The natural history of temporal variant frontotemporal dementia
Neurology, April 26, 2005; 64(8): 1384 - 1390.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
A. Zeman
Tales from the Temporal Lobes
N. Engl. J. Med., January 13, 2005; 352(2): 119 - 121.
[Full Text] [PDF]

Home page
 NeurologyHome page
S. Joubert, O. Felician, E. Barbeau, A. Sontheimer, E. Guedj, M. Ceccaldi, and M. Poncet
Progressive prosopagnosia: Clinical and neuroimaging results
Neurology, November 23, 2004; 63(10): 1962 - 1965.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
D. A. Levy, P. J. Bayley, and L. R. Squire
The anatomy of semantic knowledge: Medial vs. lateral temporal lobe
PNAS, April 27, 2004; 101(17): 6710 - 6715.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
C. H. Halpern, G. Glosser, R. Clark, J. Gee, P. Moore, K. Dennis, C. McMillan, A. Colcher, and M. Grossman
Dissociation of numbers and objects in corticobasal degeneration and semantic dementia
Neurology, April 13, 2004; 62(7): 1163 - 1169.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. S. Snowden, J. C. Thompson, and D. Neary
Knowledge of famous faces and names in semantic dementia
Brain, April 1, 2004; 127(4): 860 - 872.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
M. Grossman, C. McMillan, P. Moore, L. Ding, G. Glosser, M. Work, and J. Gee
What's in a name: voxel-based morphometric analyses of MRI and naming difficulty in Alzheimer's disease, frontotemporal dementia and corticobasal degeneration
Brain, March 1, 2004; 127(3): 628 - 649.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
S. A. Thompson, K. Patterson, and J. R. Hodges
Left/right asymmetry of atrophy in semantic dementia: Behavioral-cognitive implications
Neurology, November 11, 2003; 61(9): 1196 - 1203.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
M. A. Lambon Ralph, K. Patterson, N. Graham, K. Dawson, and J. R. Hodges
Homogeneity and heterogeneity in mild cognitive impairment and Alzheimer's disease: a cross-sectional and longitudinal study of 55 cases
Brain, November 1, 2003; 126(11): 2350 - 2362.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
P. J. Nestor, N. L. Graham, T. D. Fryer, G. B. Williams, K. Patterson, and J. R. Hodges
Progressive non-fluent aphasia is associated with hypometabolism centred on the left anterior insula
Brain, November 1, 2003; 126(11): 2406 - 2418.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
S. Joubert, O. Felician, E. Barbeau, A. Sontheimer, J. J. Barton, M. Ceccaldi, and M. Poncet
Impaired configurational processing in a case of progressive prosopagnosia associated with predominant right temporal lobe atrophy
Brain, November 1, 2003; 126(11): 2537 - 2550.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
S Nyatsanza, T Shetty, C Gregory, S Lough, K Dawson, and J R Hodges
A study of stereotypic behaviours in Alzheimer's disease and frontal and temporal variant frontotemporal dementia
J. Neurol. Neurosurg. Psychiatry, October 1, 2003; 74(10): 1398 - 1402.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
P. Piolino, B. Desgranges, S. Belliard, V. Matuszewski, C. Lalevee, V. De La Sayette, and F. Eustache
Autobiographical memory and autonoetic consciousness: triple dissociation in neurodegenerative diseases
Brain, October 1, 2003; 126(10): 2203 - 2219.
[Abstract] [Full Text] [PDF]

Home page
 Mayo Clin Proc.Home page
D. S. Knopman, B. F. Boeve, and R. C. Petersen
Essentials of the Proper Diagnoses of Mild Cognitive Impairment, Dementia, and Major Subtypes of Dementia
Mayo Clin. Proc., October 1, 2003; 78(10): 1290 - 1308.
[Abstract] [PDF]

Home page
 JNMHome page
M.-H. Soriani-Lefevre, D. Hannequin, S. Bakchine, J.-F. Menard, A. Manrique, A. Hitzel, P.-O. Kotzki, V. Boudousq, and P. Vera
Evidence of Bilateral Temporal Lobe Involvement in Primary Progressive Aphasia: A SPECT Study
J. Nucl. Med., July 1, 2003; 44(7): 1013 - 1022.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. T. Crinion, M. A. Lambon-Ralph, E. A. Warburton, D. Howard, and R. J. S. Wise
Temporal lobe regions engaged during normal speech comprehension
Brain, May 1, 2003; 126(5): 1193 - 1201.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
G. Gainotti, A. Barbier, and C. Marra
Slowly progressive defect in recognition of familiar people in a patient with right anterior temporal atrophy
Brain, April 1, 2003; 126(4): 792 - 803.
[Abstract] [Full Text] [PDF]

Home page
 Br Med BullHome page
R. J S Wise
Language systems in normal and aphasic human subjects: functional imaging studies and inferences from animal studies
Br. Med. Bull., March 1, 2003; 65(1): 95 - 119.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M Ikeda, J Brown, A J Holland, R Fukuhara, and J R Hodges
Changes in appetite, food preference, and eating habits in frontotemporal dementia and Alzheimer's disease
J. Neurol. Neurosurg. Psychiatry, October 1, 2002; 73(4): 371 - 376.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
M. D. Kopelman
Disorders of memory
Brain, October 1, 2002; 125(10): 2152 - 2190.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
H. B. Coslett, E. M. Saffran, and J. Schwoebel
Knowledge of the human body: A distinct semantic domain
Neurology, August 13, 2002; 59(3): 357 - 363.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
H. J. Rosen, K. M. Hartikainen, W. Jagust, J. H. Kramer, B. R. Reed, J. L. Cummings, K. Boone, W. Ellis, C. Miller, and B. L. Miller
Utility of clinical criteria in differentiating frontotemporal lobar degeneration (FTLD) from AD
Neurology, June 11, 2002; 58(11): 1608 - 1615.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M D Greicius, M D Geschwind, and B L Miller
Presenile dementia syndromes: an update on taxonomy and diagnosis
J. Neurol. Neurosurg. Psychiatry, June 1, 2002; 72(6): 691 - 700.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
B. Desgranges, J.-C. Baron, C. Lalevee, B. Giffard, F. Viader, V. de la Sayette, and F. Eustache
The neural substrates of episodic memory impairment in Alzheimer's disease as revealed by FDG-PET: relationship to degree of deterioration
Brain, May 1, 2002; 125(5): 1116 - 1124.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
S. M. Pickering-Brown, A. M. T. Richardson, J. S. Snowden, A. M McDonagh, A. Burns, W. Braude, M. Baker, W.-K. Liu, S.-H. Yen, J. Hardy, et al.
Inherited frontotemporal dementia in nine British families associated with intronic mutations in the tau gene
Brain, April 1, 2002; 125(4): 732 - 751.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
H. J. Rosen, M. L. Gorno-Tempini, W. P. Goldman, R. J. Perry, N. Schuff, M. Weiner, R. Feiwell, J. H. Kramer, and B. L. Miller
Patterns of brain atrophy in frontotemporal dementia and semantic dementia
Neurology, January 22, 2002; 58(2): 198 - 208.
[Abstract] [Full Text] [PDF]

Home page
 AM J ALZHEIMERS DIS OTHER DEMENHome page
A. Kertesz and D. G. Munoz
Primary progressive aphasia: A review of the neourobiology of a common presentation of Pick complex
American Journal of Alzheimer's Disease and Other Dementias, January 1, 2002; 17(1): 30 - 36.
[Abstract] [PDF]

Home page
 NeurologyHome page
C. J. Galton, K. Patterson, K. Graham, M.A. Lambon-Ralph, G. Williams, N. Antoun, B.J. Sahakian, and J.R. Hodges
Differing patterns of temporal atrophy in Alzheimer's disease and semantic dementia
Neurology, July 24, 2001; 57(2): 216 - 225.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
M. N. Rossor
Pick's disease: A clinical overview
Neurology, June 12, 2001; 56(90004): S3 - 5.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
J. R. Hodges
Frontotemporal dementia (Pick's disease): Clinical features and assessment
Neurology, June 12, 2001; 56(90004): S6 - 10.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
P. Mychack, J. H. Kramer, K. B. Boone, and B. L. Miller
The influence of right frontotemporal dysfunction on social behavior in frontotemporal dementia
Neurology, June 12, 2001; 56(90004): S11 - 15.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
R. J. Perry and B. L. Miller
Behavior and treatment in frontotemporal dementia
Neurology, June 12, 2001; 56(90004): S46 - 51.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
J S Snowden, D Bathgate, A Varma, A Blackshaw, Z C Gibbons, and D Neary
Distinct behavioural profiles in frontotemporal dementia and semantic dementia
J. Neurol. Neurosurg. Psychiatry, March 1, 2001; 70(3): 323 - 332.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
J Calderon, R J Perry, S W Erzinclioglu, G E Berrios, T R Dening, and J R Hodges
Perception, attention, and working memory are disproportionately impaired in dementia with Lewy bodies compared with Alzheimer's disease
J. Neurol. Neurosurg. Psychiatry, February 1, 2001; 70(2): 157 - 164.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.