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Brain, Vol. 117, No. 6, 1241-1253, 1994
© 1994 Guarantors of Brain

research-article

The role of the right hemisphere in the interpretation of figurative aspects of language A positron emission tomography activation study

G. Bottini1,4,, R. Corcoran2, R. Sterzi4, E. Paulesu1,5, P. Schenone6, P. Scarpa1,7, R. S. J. Frackowiak1,3 and D. Frith1,2,3

1MRC Clinical Sciences Centre, Hammersmith Hospitalthe London, UK 2Department of Psychology, University College London London, UK 3Wellcome Department of Cognitive Neurology, National Hospital of Neurology and Neurosurgery London, UK 4Divisione Neurologia, Ospedale Niguarda Milano 5INB CNR, Istituto H San Raffaele Milano 6Glottodidattica, Libera Universita' Maria S. Assunta (LUMSA) Roma 7Facolta' di Psicologia, Universita' di Padova Padova, Italy

Correspondence to: Correspondence to: G. Bottini, MRC Clinical Sciences Centre, Hammersmith Hospital, Du Cane Road, London W12 OHS, UK

We investigated cerebral activity in six normal volunteers using PET to explore the hypothesis that the right hemisphere has a specific role in the interpretation of figurative aspects of language such as metaphors. We also mapped the anatomical structures involved in sentence comprehension. During regional cerebral blood flow measurement subjects were asked to perform three different linguistic tasks: (i) metaphorical comprehension; (ii) literal comprehension of sentences; and (iii) a lexical-decision task. We found that comprehension of sentences compared with the lexical-decision task, induced extensive activation in several regions of the left hemisphere, including the prefrontal and basal frontal cortex, the middle and inferior temporal gyri and temporal pole, the parietal cortex and the precuneus. Comprehension of metaphors was associated with similar activations in the left hemisphere, but in addition, a number of sites were activated in the right hemisphere: the prefrontal cortex, the middle temporal gyms, the precuneus and the posterior cingulate. We conclude that the interpretation of language involves widespread distributed systems bilaterally with the right hemisphere having a special role in the appreciation of metaphors.

metaphorical processing; episodic memory; semantic memory; mental imagery

Received March 9, 1994. Revised August 1, 1994. Accepted August 3, 1994.


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