Brain, Vol. 119, No. 2, 569-583, 1996
© 1996 Oxford University Press
research-article |
Impaired sensory–motor integration during grasping in writer’s cramp
1Departments of Neurology Stockholm, Sweden 2Woman and Child Health, Karolinska Hospital Stockholm, Sweden
Correspondence to:
Correspondence to: Tomas Odergren, Department of Neurology, Karolinska Hospital, Box 130, S-171 76 Stockholm, Sweden
Six subjects with writer’s cramp and six healthy control subjects were examined while lifting a small instrumented object with variable weight and friction using the precision grip. The isometric grip and load forces were sampled at 400 Hz and stored in a flexible laboratory computer system for later analysis. Quantitative measurement of vibration and temperature sensibility showed normal sensory perception in the writer’s cramp subjects. They exhibited an impaired programming of the grip-lift force co-ordination, while the ability to generate unimodal force-rate trajectories and to characterize the pattern of the force output according to memory representations of weight and friction of the object were intact. The capacity to terminate quickly the programmed grip force in lifts erroneously programmed too high was impaired. Writer’s cramp subjects also employed excessive grip force during the static phase of the lift, and some patients had a short grip force latency after sudden unpredicted load increases, indicating a disinhibited spinal reflex response. The results indicate an impaired capacity in writer’s cramp subjects to integrate sensory information in the motor programming and force regulation during precision grip tasks, despite a normal sensibility.
writer’s cramp; dystonia; sensory-motor integration; precision grip
Received September 25, 1995. Accepted November 6, 1995.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  S. M. Schabrun, C. M. Stinear, W. D. Byblow, and M. C. Ridding Normalizing Motor Cortex Representations in Focal Hand Dystonia Cereb Cortex, September 1, 2009; 19(9): 1968 - 1977. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Cimatti, D. P Schwartz, F. Bourdain, S. Meunier, J.-P. Bleton, M. Vidailhet, B. Renault, and L. Garnero Time-frequency analysis reveals decreased high-frequency oscillations in writer's cramp Brain, January 1, 2007; 130(1): 198 - 205. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J Prodoehl, D M Corcos, and D E Vaillancourt Effects of focal hand dystonia on visually guided and internally guided force control J. Neurol. Neurosurg. Psychiatry, August 1, 2006; 77(8): 909 - 914. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Dresel, B. Haslinger, F. Castrop, A. M. Wohlschlaeger, and A. O. Ceballos-Baumann Silent event-related fMRI reveals deficient motor and enhanced somatosensory activation in orofacial dystonia Brain, January 1, 2006; 129(1): 36 - 46. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D A Nowak, K Rosenkranz, H Topka, and J Rothwell Disturbances of grip force behaviour in focal hand dystonia: evidence for a generalised impairment of sensory-motor integration? J. Neurol. Neurosurg. Psychiatry, July 1, 2005; 76(7): 953 - 959. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Delmaire, A. Krainik, S. Tezenas du Montcel, E. Gerardin, S. Meunier, J. -F. Mangin, S. Sangla, L. Garnero, M. Vidailhet, and S. Lehericy Disorganized somatotopy in the putamen of patients with focal hand dystonia Neurology, April 26, 2005; 64(8): 1391 - 1396. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Quartarone, S. Bagnato, V. Rizzo, H. R. Siebner, V. Dattola, A. Scalfari, F. Morgante, F. Battaglia, M. Romano, and P. Girlanda Abnormal associative plasticity of the human motor cortex in writer's cramp Brain, December 1, 2003; 126(12): 2586 - 2596. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Wenzelburger, B.-R. Zhang, S. Pohle, S. Klebe, D. Lorenz, J. Herzog, H. Wilms, G. Deuschl, and P. Krack Force overflow and levodopa-induced dyskinesias in Parkinson's disease Brain, April 1, 2002; 125(4): 871 - 879. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Serrien, A. C. Nirkko, T. J. Loher, K.-O. Lovblad, J.-M. Burgunder, and M. Wiesendanger Movement control of manipulative tasks in patients with Gilles de la Tourette syndrome Brain, February 1, 2002; 125(2): 290 - 300. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. H. Ehrsson, A. Fagergren, and H. Forssberg Differential Fronto-Parietal Activation Depending on Force Used in a Precision Grip Task: An fMRI Study J Neurophysiol, June 1, 2001; 85(6): 2613 - 2623. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Tinazzi, A. Priori, L. Bertolasi, E. Frasson, F. Mauguiere, and A. Fiaschi Abnormal central integration of a dual somatosensory input in dystonia : Evidence for sensory overflow Brain, January 1, 2000; 123(1): 42 - 50. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Rome and R. A. Grunewald Abnormal perception of vibration-induced illusion of movement in dystonia Neurology, November 1, 1999; 53(8): 1794 - 1794. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Yazawa, A. Ikeda, R. Kaji, K. Terada, T. Nagamine, K.-i. Toma, T. Kubori, J. Kimura, and H. Shibasaki1 Abnormal cortical processing of voluntary muscle relaxation in patients with focal hand dystonia studied by movement-related potentials Brain, July 1, 1999; 122(7): 1357 - 1366. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Forssberg, A.-C. Eliasson, C. Redon-Zouitenn, E. Mercuri, and L. Dubowitz Impaired grip–lift synergy in children with unilateral brain lesions Brain, June 1, 1999; 122(6): 1157 - 1168. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. R. Siebner, J. M. Tormos, A. O. C. Baumann, C. Auer, M. D. Catala, B. Conrad, and A. Pascual-Leone Low-frequency repetitive transcranial magnetic stimulation of the motor cortex in writer's cramp Neurology, February 1, 1999; 52(3): 529 - 529. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. J. Feiwell, K. J. Black, L. A. McGee-Minnich, A. Z. Snyder, A.-M. MacLeod, and J. S. Perlmutter Diminished regional cerebral blood flow response to vibration in patients with blepharospasm Neurology, January 1, 1999; 52(2): 291 - 291. [Abstract] [Full Text] [PDF]
|
|