Brain, Vol. 119, No. 5, 1617-1625, 1996
© 1996 Guarantors of Brain
research-article |
Regional brain activity during working memory tasks
1Cyclotron Research Centre, University of Liège Belgium 2Department of Neurology, University of Liège Belgium 3Department of Neuropsychology, University of Liège Belgium
Correspondence to:
E. Salmon, MD, Cyclotron Research Centre, B30 Sart Tilman, 4000 Liège, Belgium.
The first aim of our PET study was to replicate previous findings concerning the brain areas activated by a verbal working memory task. The second aim was to specify the neural basis of the central executive, using a task of working memory updating. Our data confirm that the lower left supramarginal gyrus and premotor area are the key regions subserving short-term verbal memory processes. They also suggest that the updating memory task is related to middorsolateral prefrontal activation, most probably responsible for the updating function of the central executive. An unexpected, predominantly right activation occurred in the inferior parietal region during the verbal memory updating task, which we related to a visuospatial strategy used to maintain the information in short-term memory. A third purpose was to explore the brain regions activated by a nonverbal, visual memory task, and our results confirm the importance of the superior occipital gyrus in the visual shortterm memory.
working memory; central executive; PET
Received March 18, 1996. Accepted May 10, 1996.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  F. Peters, F. Collette, C. Degueldre, V. Sterpenich, S. Majerus, and E. Salmon The neural correlates of verbal short-term memory in Alzheimer's disease: an fMRI study Brain, July 1, 2009; 132(7): 1833 - 1846. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. S. Grabell and R. A. Knight Examining Childhood Abuse Patterns and Sensitive Periods in Juvenile Sexual Offenders Sexual Abuse: A Journal of Research and Treatment, June 1, 2009; 21(2): 208 - 222. [Abstract] [PDF]
|
|
|
|
|
|
N. Abe, T. Fujii, K. Hirayama, A. Takeda, Y. Hosokai, T. Ishioka, Y. Nishio, K. Suzuki, Y. Itoyama, S. Takahashi, et al. Do parkinsonian patients have trouble telling lies? The neurobiological basis of deceptive behaviour Brain, May 1, 2009; 132(5): 1386 - 1395. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Lohmann and M. W. Riepe Neurotoxic Effects of Repetitive Inhibition of Oxidative Phosphorylation in Young Adults Surfacing With Deficits of Spatial Learning in Old Age J. Gerontol. A Biol. Sci. Med. Sci., December 1, 2007; 62(12): 1352 - 1356. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. K. Roth, J. T. Serences, and S. M. Courtney Neural System for Controlling the Contents of Object Working Memory in Humans Cereb Cortex, November 1, 2006; 16(11): 1595 - 1603. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Hellweg, P. Lohmann, R. Huber, A. Kuhl, and M. W. Riepe Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signaling as a biological marker of early impairment Learn. Mem., January 1, 2006; 13(1): 63 - 71. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Bitan, J. R. Booth, J. Choy, D. D. Burman, D. R. Gitelman, and M.-M. Mesulam Shifts of Effective Connectivity within a Language Network during Rhyming and Spelling J. Neurosci., June 1, 2005; 25(22): 5397 - 5403. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. D. Selemon, J. Mrzljak, J. E. Kleinman, M. M. Herman, and P. S. Goldman-Rakic Regional Specificity in the Neuropathologic Substrates of Schizophrenia: A Morphometric Analysis of Broca's Area 44 and Area 9 Arch Gen Psychiatry, January 1, 2003; 60(1): 69 - 77. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C Christodoulou, J DeLuca, J H Ricker, N K Madigan, B M Bly, G Lange, A J Kalnin, W-C Liu, J Steffener, B J Diamond, et al. Functional magnetic resonance imaging of working memory impairment after traumatic brain injury J. Neurol. Neurosurg. Psychiatry, August 1, 2001; 71(2): 161 - 168. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Garavan, T.J. Ross, S.-J. Li, and E.A. Stein A Parametric Manipulation of Central Executive Functioning Cereb Cortex, June 1, 2000; 10(6): 585 - 592. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. R. Postle, J. S. Berger, and M. D'Esposito Functional neuroanatomical double dissociation of mnemonic and executive control processes contributing to working memory performance PNAS, October 26, 1999; 96(22): 12959 - 12964. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I.C. Wright, T. Sharma, Z.R. Ellison, P.K. McGuire, K.J. Friston, M.J. Brammer, R.M. Murray, and E.T. Bullmore Supra-regional Brain Systems and the Neuropathology of Schizophrenia Cereb Cortex, June 1, 1999; 9(4): 366 - 378. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Bunge, T. Klingberg, R. B. Jacobsen, and J. D. E. Gabrieli A resource model of the neural basis of executive working memory PNAS, March 28, 2000; 97(7): 3573 - 3578. [Abstract] [Full Text] [PDF]
|
|