Brain, Vol 120, Issue 6 939-953, Copyright © 1997 by Oxford University Press
Y Inoue, T Fujiwara, K Matsuda, H Kubota, M Tanaka, K Yagi, K Yamamori and Y Takahashi
Six cases of epilepsy associated with ring chromosome 20 are presented. The
study of these cases and 20 cases reported in the literature revealed that
they constitute a distinct epileptic syndrome: frequent seizures consisting
of a prolonged confusional state, with or without additional motor
seizures, and an ictal EEG pattern of long-lasting bilateral paroxysmal
high-voltage slow waves with occasional spikes. Neurological examination
results were normal, and neuroimaging studies often failed to disclose a
brain lesion. The seizures were resistant to antiepileptic drug therapy.
Comparison of the electroclinical features of nonconvulsive status
epilepticus in six patients with and four patients without ring chromosome
20 revealed that the group with the chromosomal anomaly had more frequent,
comparatively brief episodes of confusion associated with a less prominent
spike component on the EEG. We propose that epilepsy associated with ring
chromosome 20 constitutes a new syndrome that may provide an opportunity to
scrutinize a genetic mechanism of epilepsy.
REVIEWS
Ring chromosome 20 and nonconvulsive status epilepticus. A new epileptic syndrome
National Epilepsy Center, Shizuoka Higashi Hospital, Japan.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  V. Bouilleret, F. Semah, A. Biraben, D. Taussig, F. Chassoux, A. Syrota, and M.-J. Ribeiro Involvement of the Basal Ganglia in Refractory Epilepsy: An 18F-Fluoro-L-DOPA PET Study Using 2 Methods of Analysis J. Nucl. Med., March 1, 2005; 46(3): 540 - 547. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Biraben, F. Semah, M. -J. Ribeiro, G. Douaud, P. Remy, and A. Depaulis PET evidence for a role of the basal ganglia in patients with ring chromosome 20 epilepsy Neurology, July 13, 2004; 63(1): 73 - 77. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N Tanaka, K Kamada, and F Takeuchi Ictal magnetoencephalographic study in a patient with ring 20 syndrome J. Neurol. Neurosurg. Psychiatry, March 1, 2004; 75(3): 488 - 490. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Chawla, R. Sucholeiki, C. Jones, and K. Silver Intractable Epilepsy With Ring Chromosome 20 Syndrome Treated With Vagal Nerve Stimulation: Case Report and Review of the Literature J Child Neurol, October 1, 2002; 17(10): 778 - 780. [Abstract] [PDF]
|
|
|
|
|
|
W. G. Mitchell Status Epilepticus and Acute Serial Seizures in Children J Child Neurol, January 1, 2002; 17(1_suppl): S36 - S43. [Abstract] [PDF]
|
|
|
|
|
|
P. B. Augustijn, J. Parra, C. H. Wouters, P. Joosten, D. Lindhout, and W. van Emde Boas Ring chromosome 20 epilepsy syndrome in children: Electroclinical features Neurology, September 25, 2001; 57(6): 1108 - 1111. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Thomas, B. Zifkin, O. Migneco, C. Lebrun, J. Darcourt, and F. Andermann Nonconvulsive status epilepticus of frontal origin Neurology, April 1, 1999; 52(6): 1174 - 1174. [Abstract] [Full Text]
|
|