Brain, Vol 121, Issue 2 253-264, Copyright © 1998 by Oxford University Press
MJ Catalan, M Honda, RA Weeks, LG Cohen and M Hallett
The brain regions activated by simple repetitive and sequential finger
movements of different length were localized by measuring regional cerebral
blood flow (rCBF) with PET. The experimental design consisted of finger
movements cued by auditory pacing at 0.5 Hz. In all conditions of different
sequence length the contralateral primary sensorimotor and premotor cortex,
supplementary motor area and ipsilateral cerebellar cortex were activated.
These areas showed a large increase in activation from rest to simple
repetitive movement, and a further increase with the shortest sequence,
suggesting an executive role in running sequences. The ipsilateral premotor
area (Brodmann area 6), bilateral posterior parietal areas (Brodmann area
7) and precuneus showed an increase in rCBF related only to the length of
the sequences, without any change from rest to simple repetitive movement.
These areas are more selectively related to sequence performance. This
finding is consistent with the hypothesis that these areas function in the
storage of motor sequences in spatial working memory. Our results suggest
that sequential finger movements recruit discrete sets of brain areas with
different functions.
ARTICLES
The functional neuroanatomy of simple and complex sequential finger movements: a PET study
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-1428, USA.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  J. A. Grahn and J. B. Rowe Feeling the Beat: Premotor and Striatal Interactions in Musicians and Nonmusicians during Beat Perception J. Neurosci., June 10, 2009; 29(23): 7540 - 7548. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. J. Seo, W. Z. Rymer, and D. G. Kamper Delays in Grip Initiation and Termination in Persons With Stroke: Effects of Arm Support and Active Muscle Stretch Exercise J Neurophysiol, June 1, 2009; 101(6): 3108 - 3115. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. J. Wisneski, N. Anderson, G. Schalk, M. Smyth, D. Moran, and E. C. Leuthardt Unique Cortical Physiology Associated With Ipsilateral Hand Movements and Neuroprosthetic Implications Stroke, December 1, 2008; 39(12): 3351 - 3359. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. D. Schaechter and K. L. Perdue Enhanced Cortical Activation in the Contralesional Hemisphere of Chronic Stroke Patients in Response to Motor Skill Challenge Cereb Cortex, March 1, 2008; 18(3): 638 - 647. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Jubault, C. Ody, and E. Koechlin Serial Organization of Human Behavior in the Inferior Parietal Cortex J. Neurosci., October 10, 2007; 27(41): 11028 - 11036. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Davare, J Duque, Y Vandermeeren, J-L Thonnard, and E Olivier Role of the Ipsilateral Primary Motor Cortex in Controlling the Timing of Hand Muscle Recruitment Cereb Cortex, February 1, 2007; 17(2): 353 - 362. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Lotze, J. Markert, P. Sauseng, J. Hoppe, C. Plewnia, and C. Gerloff The role of multiple contralesional motor areas for complex hand movements after internal capsular lesion. J. Neurosci., May 31, 2006; 26(22): 6096 - 6102. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. M. Carey, D. F. Abbott, G. F. Egan, G. J. O'Keefe, G. D. Jackson, J. Bernhardt, and G. A. Donnan Evolution of Brain Activation with Good and Poor Motor Recovery after Stroke Neurorehabil Neural Repair, March 1, 2006; 20(1): 24 - 41. [Abstract] [PDF]
|
|
|
|
 |
|
 C. Gerloff, K. Bushara, A. Sailer, E. M. Wassermann, R. Chen, T. Matsuoka, D. Waldvogel, G. F. Wittenberg, K. Ishii, L. G. Cohen, et al. Multimodal imaging of brain reorganization in motor areas of the contralesional hemisphere of well recovered patients after capsular stroke Brain, March 1, 2006; 129(3): 791 - 808. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Lehericy, E. Bardinet, L. Tremblay, P.-F. Van de Moortele, J.-B. Pochon, D. Dormont, D.-S. Kim, J. Yelnik, and K. Ugurbil Motor control in basal ganglia circuits using fMRI and brain atlas approaches Cereb Cortex, February 1, 2006; 16(2): 149 - 161. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Saarinen, H. Laaksonen, T. Parviainen, and R. Salmelin Motor Cortex Dynamics in Visuomotor Production of Speech and Non-speech Mouth Movements Cereb Cortex, February 1, 2006; 16(2): 212 - 222. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. Quaney, S. Perera, R. Maletsky, C. W. Luchies, and R. J. Nudo Impaired Grip Force Modulation in the Ipsilesional Hand after Unilateral Middle Cerebral Artery Stroke Neurorehabil Neural Repair, December 1, 2005; 19(4): 338 - 349. [Abstract] [PDF]
|
|
|
|
|
|
P.C. Fletcher, O. Zafiris, C.D. Frith, R.A.E. Honey, P.R. Corlett, K. Zilles, and G.R. Fink On the Benefits of not Trying: Brain Activity and Connectivity Reflecting the Interactions of Explicit and Implicit Sequence Learning Cereb Cortex, July 1, 2005; 15(7): 1002 - 1015. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Zadikoff and A. E. Lang Apraxia in movement disorders Brain, July 1, 2005; 128(7): 1480 - 1497. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Strangman, W. C. Heindel, J. A. Anderson, and J. P. Sutton Learning Motor Sequences with and without Knowledge of Governing Rules Neurorehabil Neural Repair, June 1, 2005; 19(2): 93 - 114. [Abstract] [PDF]
|
|
|
|
|
|
L. M. Carey, D. F. Abbott, G. F. Egan, J. Bernhardt, and G. A. Donnan Motor Impairment and Recovery in the Upper Limb After Stroke: Behavioral and Neuroanatomical Correlates Stroke, March 1, 2005; 36(3): 625 - 629. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Wu and M. Hallett The influence of normal human ageing on automatic movements J. Physiol., January 15, 2005; 562(2): 605 - 615. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Tanaka, M. Honda, and N. Sadato Modality-Specific Cognitive Function of Medial and Lateral Human Brodmann Area 6 J. Neurosci., January 12, 2005; 25(2): 496 - 501. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M Makuuchi, T Kaminaga, and M Sugishita Brain activation during ideomotor praxis: imitation and movements executed by verbal command J. Neurol. Neurosurg. Psychiatry, January 1, 2005; 76(1): 25 - 33. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. E. Martin, B. J. MacIntosh, R. C. Smith, A. M. Barr, T. K. Stevens, J. S. Gati, and R. S. Menon Cerebral Areas Processing Swallowing and Tongue Movement Are Overlapping but Distinct: A Functional Magnetic Resonance Imaging Study J Neurophysiol, October 1, 2004; 92(4): 2428 - 2493. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. J. Jantzen, B. Anderson, F. L Steinberg, and J. A. S. Kelso A Prospective Functional MR Imaging Study of Mild Traumatic Brain Injury in College Football Players AJNR Am. J. Neuroradiol., May 1, 2004; 25(5): 738 - 745. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Wu, K. Kansaku, and M. Hallett How Self-Initiated Memorized Movements Become Automatic: A Functional MRI Study J Neurophysiol, April 1, 2004; 91(4): 1690 - 1698. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Ben-Shaul, R. Drori, I. Asher, E. Stark, Z. Nadasdy, and M. Abeles Neuronal Activity in Motor Cortical Areas Reflects the Sequential Context of Movement J Neurophysiol, April 1, 2004; 91(4): 1748 - 1762. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Kobayashi, S. Hutchinson, H. Theoret, G. Schlaug, and A. Pascual-Leone Repetitive TMS of the motor cortex improves ipsilateral sequential simple finger movements Neurology, January 13, 2004; 62(1): 91 - 98. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. S. Ward, M. M. Brown, A. J. Thompson, and R. S. J. Frackowiak Neural correlates of motor recovery after stroke: a longitudinal fMRI study Brain, November 1, 2003; 126(11): 2476 - 2496. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. S. Ward, M. M. Brown, A. J. Thompson, and R. S. J. Frackowiak Neural correlates of outcome after stroke: a cross-sectional fMRI study Brain, June 1, 2003; 126(6): 1430 - 1448. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Taniwaki, A. Okayama, T. Yoshiura, Y. Nakamura, Y. Goto, J.-i. Kira, and S. Tobimatsu Reappraisal of the Motor Role of Basal Ganglia: A Functional Magnetic Resonance Image Study J. Neurosci., April 15, 2003; 23(8): 3432 - 3438. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. S. Ward and R. S. J. Frackowiak Age-related changes in the neural correlates of motor performance Brain, April 1, 2003; 126(4): 873 - 888. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Hanakawa, I. Immisch, K. Toma, M. A. Dimyan, P. Van Gelderen, and M. Hallett Functional Properties of Brain Areas Associated With Motor Execution and Imagery J Neurophysiol, February 1, 2003; 89(2): 989 - 1002. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. K. Goerendt, C. Messa, A. D. Lawrence, P. M. Grasby, P. Piccini, and D. J. Brooks Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study Brain, February 1, 2003; 126(2): 312 - 325. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Hanakawa, M. Honda, N. Sawamoto, T. Okada, Y. Yonekura, H. Fukuyama, and H. Shibasaki The Role of Rostral Brodmann Area 6 in Mental-operation Tasks: an Integrative Neuroimaging Approach Cereb Cortex, November 1, 2002; 12(11): 1157 - 1170. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Staudt, W. Grodd, C. Gerloff, M. Erb, J. Stitz, and I. Krageloh-Mann Two types of ipsilateral reorganization in congenital hemiparesis: A TMS and fMRI study Brain, October 1, 2002; 125(10): 2222 - 2237. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Krings, R. Topper, K. Willmes, M. H.T. Reinges, J. M. Gilsbach, and A. Thron Activation in primary and secondary motor areas in patients with CNS neoplasms and weakness Neurology, February 12, 2002; 58(3): 381 - 390. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Haslinger, P. Erhard, N. Kampfe, H. Boecker, E. Rummeny, M. Schwaiger, B. Conrad, and A. O. Ceballos-Baumann Event-related functional magnetic resonance imaging in Parkinson's disease before and after levodopa Brain, March 1, 2001; 124(3): 558 - 570. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Gerardin, A. Sirigu, S. Lehericy, J.-B. Poline, B. Gaymard, C. Marsault, Y. Agid, and D. Le Bihan Partially Overlapping Neural Networks for Real and Imagined Hand Movements Cereb Cortex, November 1, 2000; 10(11): 1093 - 1104. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Sailer, J. Dichgans, and C. Gerloff The influence of normal aging on the cortical processing of a simple motor task Neurology, October 10, 2000; 55(7): 979 - 985. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. C. Leiguarda and C. D. Marsden Limb apraxias: Higher-order disorders of sensorimotor integration Brain, May 1, 2000; 123(5): 860 - 879. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-P. Deiber, M. Honda, V. Ibanez, N. Sadato, and M. Hallett Mesial Motor Areas in Self-Initiated Versus Externally Triggered Movements Examined With fMRI: Effect of Movement Type and Rate J Neurophysiol, June 1, 1999; 81(6): 3065 - 3077. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Catalan, K. Ishii, M. Honda, A. Samii, and M. Hallett A PET study of sequential finger movements of varying length in patients with Parkinson's disease Brain, March 1, 1999; 122(3): 483 - 495. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. T. Grafton, E. Hazeltine, and R. B. Ivry Abstract and Effector-Specific Representations of Motor Sequences Identified with PET J. Neurosci., November 15, 1998; 18(22): 9420 - 9428. [Abstract] [Full Text] [PDF]
|
|