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Brain Advance Access originally published online on July 15, 2006
Brain 2006 129(10):2533-2553; doi:10.1093/brain/awl171
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© The Author (2006). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Review Articles

Music and the brain: disorders of musical listening

Lauren Stewart1,2,3, Katharina von Kriegstein1,3, Jason D. Warren4 and Timothy D. Griffiths1,3

1 Auditory Group, Newcastle University Newcastle upon Tyne, London, UK 2 Institute of Cognitive Neuroscience, University College London London, UK 3 Wellcome Department of Imaging Neuroscience, University College London London, UK 4 Dementia Research Centre, Institute of Neurology, University College London London, UK

Correspondence to: Tim Griffiths, Cognitive Neurology Clinic, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK E-mail: t.d.griffiths{at}ncl.ac.uk

The study of the brain bases for normal musical listening has advanced greatly in the last 30 years. The evidence from basic and clinical neuroscience suggests that listening to music involves many cognitive components with distinct brain substrates. Using patient cases reported in the literature, we develop an approach for understanding disordered musical listening that is based on the systematic assessment of the perceptual and cognitive analysis of music and its emotional effect. This approach can be applied both to acquired and congenital deficits of musical listening, and to aberrant listening in patients with musical hallucinations. Both the bases for normal musical listening and the clinical assessment of disorders now have a solid grounding in systems neuroscience.

Key Words: brain disorders; lesions; listening; music

Abbreviations: HG, Heschl's gyrus; MBEA, Montreal battery for the evaluation of amusia; MEG, magnetoencephalography; PAC, primary auditory cortex; PT, planum temporale; SPET, single photon emission tomography

Received February 14, 2006. Revised May 8, 2006. Accepted May 31, 2006.


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