Brain, Vol. 53, No. 3, 327-343, 1930
© 1930 Guarantors of Brain
research-article |
THE INFLUENCE OF UNILATERAL DESTRUCTION OF THE VESTIBULAR NUCLEI UPON POSTURE AND THE KNEE-JERK1
Laboratory of Physiology Oxford
Experimental lesions of the vestibular nuclei in normal animals cause hypotonia on the side of the lesions, forced rolling movements to that side. If decerebrated after an interval of three weeks, the rigidity and stretch reflexes are greatly diminished on the injured side, and the knee-jerk is more readily inhibited. Marchi staining of the cord in such animals has shown extensive degeneration of the homo-lateral vestibulospinal pathway and slight degeneration in the crossed vestibulospinal tract.
Acute lesions of Deiters' area after decerebration also cause great diminution of rigidity on the same side and increased susceptibility of the knee-jerk to inhibition.
We conclude that the nucleus of Deiters and the direct spinal pathway to which it gives rise is chiefly responsible for the differences between the decerebrate and the spinal condition, and hence its integrity is essential for preventing spinal shock.
.
1 A preliminary note under the same title has appeared in the Journal of Physiology (1930, 70, Proc., xxii).
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  K. Matsuyama and T. Drew Vestibulospinal and Reticulospinal Neuronal Activity During Locomotion in the Intact Cat. I. Walking on a Level Surface J Neurophysiol, November 1, 2000; 84(5): 2237 - 2256. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. H. COOK and G. W. STAVRAKY A CEREBELLAR COMPONENT OF CONVULSIVE MANIFESTATIONS Arch Neurol Psychiatry, December 1, 1952; 68(6): 741 - 754. [Abstract] [PDF]
|
|
|
|
|
|
K. H. ABBOTT ABDOMINAL RIGIDITY: A Symptom of Concussion of the Spinal Cord Arch Neurol Psychiatry, February 1, 1947; 57(2): 220 - 227. [Abstract] [PDF]
|
|
|
|
 |
|
 H. O'NEILL A STUDY OF THE ATTITUDINAL REFLEXES OF MAGNUS AND de KLEIJN IN THALAMIC MAN Arch Otolaryngol Head Neck Surg, March 1, 1946; 43(3): 243 - 282. [Abstract] [PDF]
|
|
|
|
|
|
R. L. SWANK and M. PRADOS AVIAN THIAMINE DEFICIENCY: II. PATHOLOGIC CHANGES IN THE BRAIN AND CRANIAL NERVES (ESPECIALLY THE VESTIBULAR) AND THEIR RELATION TO THE CLINICAL BEHAVIOR Arch Neurol Psychiatry, January 1, 1942; 47(1): 97 - 131. [Abstract] [PDF]
|
|
|
|
|
|
P. C. BUCY STUDIES ON THE HUMAN NEUROMUSCULAR MECHANISM: II. EFFECT OF VENTROMEDIAL CHORDOTOMY ON MUSCULAR SPASTICITY IN MAN Arch Neurol Psychiatry, October 1, 1938; 40(4): 639 - 662. [Abstract] [PDF]
|
|
|
|
|
|
W. R. INGRAM and S. W. RANSON EFFECTS OF LESIONS IN THE RED NUCLEI IN CATS Arch Neurol Psychiatry, September 1, 1932; 28(3): 483 - 512. [Abstract] [PDF]
|
|
|
|
|
|
J. F. FULTON, E. G. T. LIDDELL, and D. McK. RIOCH RELATION OF THE CEREBRUM TO THE CEREBELLUM: I. CEREBELLAR TREMOR IN THE CAT AND ITS ABSENCE AFTER REMOVAL OF THE CEREBRAL HEMISPHERES Arch Neurol Psychiatry, September 1, 1932; 28(3): 542 - 570. [Abstract] [PDF]
|
|