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Brain, Vol. 123, No. 2, 407-408, February 2000
© 2000 Oxford University Press

Book reviews

CHRONIC FATIGUE AND ITS SYNDROMES.

.

Dr Meirion Llewelyn

Department of Medicine and Infectious Diseases, University Hospital of Wales, Cardiff, UK

Since the initial definition of chronic fatigue syndrome in 1988, there has been a huge amount of interest in the subject, especially as fatigue is the second most common complaint in general medical out-patient clinics. The sheer variety of specialists researching into fatigue is remarkable, and includes neurologists, psychiatrists, psychologists, infectious diseases physicians, microbiologists, immunologists, paediatricians, historians and sociologists.

Over the past 10 years, fatigue has risen in prominence from having little said about it at all in the medical literature to being an international talking point. How did this occur? In 1976 a group of doctors interested in the 1955 Royal Free Hospital outbreak of fatigue formed a group interested in epidemic fatigue. Sporadic cases without neurological signs gradually became of more interest and epidemics became very rare. By the 1980s, interest had shifted . . . [Full Text of this Article]

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