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Brain, Vol. 123, No. 4, 847-848, April 2000
© 2000 Oxford University Press

Book Reviews

CEREBRAL ISCHEMIA: MOLECULAR AND CELLULAR PATHOPHYSIOLOGY.

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Dr P. M. Cox

Department of Histopathology, Imperial College School of Medicine, London, UK

The book aims to deal with the mechanisms underlying the neuronal dysfunction which results from loss of cerebral blood/oxygen supply. The book is divided into three parts and is a series of review articles by different authors with expertise in their specific fields.

Part I is an overview of the subject. As such it is a rapid but helpful review of the mechanisms underlying cerebral ischaemic damage. The chapter starts with a look at the haemodynamic changes occurring in a focal cerebral infarct which result in a central ischaemic core and a less severely injured penumbra. There is then a brief section describing the effects on the various cellular elements of the brain—neural, . . . [Full Text of this Article]

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