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Brain, Vol. 124, No. 5, 1054-1055, May 2001
© 2001 Oxford University Press

Book reviews

CEREBRAL AMYLOID ANGIOPATHY IN ALZHEIMER'S DISEASE AND RELATED DISORDERS.

By Marcel M. Verbeel, Robert M. W. de Waal and Harry V. Vinters. 2000. Dordrecht: Kluwer Academic Publishers. Price £90. Pp. 384. ISBN 0-79-236366-3.

Alistair Lammie

Pathology Directorate, University Hospital of Wales, Cardiff, UK

Cerebral amyloid angiopathy (CAA) is the accumulation of leptomeningeal and cortical vessel amyloid in the ageing brain. It exists in familial and sporadic forms, is associated with a variety of stroke subtypes, in particular recurrent lobar haemorrhages, and is a pathological feature in over 80% of Alzheimer disease brains. This multi-author text aims to weave together the threads of what is known about this common age-related vasculopathy at clinical, pathological, molecular and genetic levels.

The 20 chapters are divided into four sections and each chapter broken down into manageable, bite-sized portions. Section 1 (Clinical aspects of CAA and CAA-related haemorrhage) begins with a . . . [Full Text of this Article]


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