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Brain, Vol. 126, No. 12, 2571-2572, December 2003
© 2003 Guarantors of Brain
doi: 10.1093/brain/awg290

Editorial

Focal hand dystonia – a disorder of neuroplasticity?

Joseph Classen1

1 Motor Control Laboratory, Department of Neurology, University of Würzburg, Germany

The first 10% of the full text of this article appears below.

The term dystonia collectively refers to a heterogeneous group of movement disorders characterized by sustained involuntary muscle contractions that result from co-contracting antagonistic muscles and overflow into extraneous muscles (Hallett, 1998Go). Like other types of focal dystonias, writer’s cramp develops in the absence of known structural changes in the nervous system and it often requires extensive repetition of movements to emerge. The pathophysiology of dystonia has been shown to comprise abnormalities in both motor and somatosensory systems.

Neuronal representations are believed to be shaped by prior experience through physiological processes commonly referred to as neuroplasticity. Numerous studies have revealed that neuronal representations may be altered in . . . [Full Text of this Article]

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