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Brain 2004 127(10):2151-2152; doi:10.1093/brain/awh306
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Brain Vol. 127 No. 10 © Guarantors of Brain 2004; all rights reserved

Scientific Commentary

Action myoclonus–renal failure syndrome: the definitive clinico-pathological description

Peter Brown

Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK

The first 10% of the full text of this article appears below.

The causes of myoclonus are protean and often obscure; none more obscure than the action myoclonus–renal failure (AMRF) syndrome reported in four French Canadian patients from the province of Québec by Andermann et al. in 1986Go. In their current paper, Andermann and colleagues transform this condition from a local rarity to one of global significance, identified in families from Canada, the USA, Cuba, Europe and Australia (Badhwar et al., 2004Go). Patients in . . . [Full Text of this Article]


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