Brain, Vol. 127, No. 4, 721-722, 2004
© 2004 Guarantors of Brain
doi: 10.1093/brain/awh164
Oscillatory activity in the basal ganglia—relationship to normal physiology and pathophysiology
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There is mounting evidence that rhythmic brain oscillatory rhythms play important roles in processes such as perception, motor action and conscious experience, and that disruption or increases of activity in various oscillatory networks may be an important factor in mediating some of the symptoms associated with neurological diseases (Llinas et al., 1999
; Bevan et al., 2002). Rhythmic brain activity is of course well known from the EEG, where several different frequency ranges of oscillatory activity have been well characterized, the best known being the alpha rhythm that is generally observed when the eyes are closed. The oscillatory activity is usually identified and studied in cortical local field potentials (LFPs) and EEG, and reflects local rhythmic
1 Department of Physiology, University of Toronto, Toronto, Ontario, Canada 2 Department of Physiology, The Hebrew University Hadassah Medical School, The Hebrew University, Jerusalem, Israel
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