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Editorial
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In 1965, we published a paper by Norman Geschwind (1926–1984) on ‘Disconnection syndromes in animals and man’ (Brain 1965; 88: 237–294 and 585–644). Merely to describe this as a landmark paper is not to do the scholarship justice. ‘Disconnection syndromes in animals and man’ illuminated otherwise incomprehensible neurological syndromes, but the exposition also allowed the reader to consider rival concepts on how the cerebrum is organized and to ponder the strictly disconnectionist formulation that Geschwind proposed to explain bizarre clinical phenomenology. It seemed so simple to understand that occlusion of the left posterior cerebral artery causes a right homonymous hemianopia and, at the same time, lesions the posterior part (splenium) of the corpus callosum thus isolating an intact right visual cortex from the left angular gyrus needed to decode visual engrams, but leaving unaffected the ability to generate graphemes already learned, thus resulting in alexia without agraphia. Geschwind presented
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