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Observations on intracranial aneurysms. By R. W. Ross Russell. (From the Neurological Unit and Mallory Institute of Pathology, Boston City Hospital and the Department of Neurology, Harvard Medical School.) Brain 1963; 86: 425–442 with plates xxxvii–xl.
In the early 1960s, Ralph Ross Russell worked in Oxford with (Sir) George Pickering, whose principal interest at that time was the cause and effects of hypertension including what were then called ‘cerebral vascular accidents’ and which rested uneasily in a limbo between general medicine and neurology, attracting little attention from either. He recalls that Derek Denny-Brown, a former Rhodes scholar with (Sir Charles) Sherrington, visited the department and spoke on transient cerebral ischaemia, at that time attributed to vasospasm. Denny-Brown showed little evidence for this mechanism and proposed that a more likely cause was a localized reduction in the blood-flow to a compromised region of the brain due to a fall in systemic
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