© The Author (2005). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Scientific Commentary |
Histological analysis of fetal dopamine cell suspension grafts in two patients with Parkinson's disease gives promising results
| The first 10% of the full text of this article appears below. |
In this issue of Brain (pages 14981510), Mendez and collaborators report the postmortem analysis of brains from two patients with Parkinson's disease who had received grafts of brain tissue dissected from the developing ventral mesencephalic region, obtained from 6- to 9-week-old aborted fetuses, which is known to contain the appropriate type of dopamine neurones lost in these patients as a result of their disease. The most important aspect of this report is the fact that this is the first time we have been able to evaluate the outcome of so-called cell suspension grafts, a more refined cell preparation technique than has been used in the previously reported
Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A11 22466, Lund, Sweden
E-mail: deniz.kirik@med.lu.se; anders.bjorklund@med.lu.se