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Scientific Commentary |
A new cause of limbic encephalopathy
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The spectrum of antibody-associated encephalopathy seems ever increasing. In 2004 Vincent et al. described, in this journal, a series of patients with a reversible limbic encephalopathy associated with antibodies against the voltage-gated potassium channels (VGKC-Ab). In this issue, Ances et al. (2005)
have described yet another cause of limbic encephalopathy, this time a paraneoplastic disorder. Furthermore, they have suggested a classification to aid the physician in diagnosis and treatment and allow one to predict prognosis.
Beau Ances and colleagues describe seven patients with the subacute onset of a limbic encephalopathy. The
1 The Rockefeller University, 1230 York Avenue and 2 Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, USA
E-mail: posnerj@mskcc.org
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