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From the Archives
Cambridge
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Focal experimental demyelination in the central nervous system. By W.I. McDonald and T.A. Sears (From the University Department of Clinical Neurology, and the Department of Neurophysiology, Institute of Neurology, Queen Square, London). Brain 1970: 93; 575582. with The effects of experimental demyelination on conduction in the central nervous system. By W.I. McDonald and T.A. Sears (From the University Department of Clinical Neurology, and the Department of Neurophysiology, Institute of Neurology, Queen Square, London). Brain 1970: 93; 583598. with The restoration of conduction by central remyelination. By K.J. Smith, W.F. Blakemore and W.I. McDonald. (From the Institute of Neurology, Queen Square, London and the Department of Clinical Veterinary Medicine, Madingley Road, Cambridge). Brain 1981: 104; 383404.
It is obvious that when a nerve fibre disintegrates completely, conduction must cease. But Ian McDonald and Tom Sears ask: what happens to nerve impulses in the central nervous system in the context of demeyelination