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From the Archives
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Sensory radicular neuropathy associated with muscle wasting in two cases. By A.M.G. Campbell and the late H.L. Hoffman (From the Bristol Royal Hospital, Bristol, and the Royal United Hospital, Bath). Brain 1964: 87; 67–74.
First, Drs Campbell and Hoffman briefly rehearse clinical and pathological accounts of conditions manifesting as hereditary perforating ulcer of the foot since the disorder was first described in the mid-19th century French literature as acropathie ulcéro-mutilante. Little was known of the pathological substrate for this condition until Dr Derek Denny-Brown correlated primary degeneration in the dorsal root ganglia with secondary involvement of the posterior roots, peripheral nerves and posterior columns of the spinal cord in one such case—designating the condition as ‘hereditary sensory radicular neuropathy’ (Denny-Brown D. Hereditary sensory radicular neuropathy Journal of Neurology Neurosurgery and Psychiatry 1951: 14; 237–252). This report was based on one of 10 affected individuals from a family first reported 30
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