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Brain 2007 130(6):1449-1452; doi:10.1093/brain/awm115
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© The Author (2007). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

The structure and functions of the cerebellum examined by a new method. By Sir Victor Horsley, FRS, FRCS and R.H. Clarke, MA, MB. Brain 1908: 31; 45–124.

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Robert Clarke and Victor Horsley seem an unlikely pair: the former a sportsman being a good judge of a horse, a keen huntsman, a first-rate shot, excellent cricketer and golfer, and a raconteur mainly of ghost-stories whose scientific interests were equally wide-ranging; the latter a pioneer of neurological surgery whose later life was increasingly distracted by controversial excursions into suffragette politics, the defence of vivisection, and evangelical patronage of the National Temperance League; but they shared an interest in gadgets.

Horsley and Clarke start by debating whether or not the cerebellar cortex is directly connected to the peduncles and spinal cord. Marchi had described a descending cerebello-spinal pathway: Ramon y Cajal referred ambiguously to a via descendente and illustrated fibres in the superior cerebellar peduncle derived from the cortex; Probst correlated fibre loss in the peduncles with the amount of damage to cerebellar nuclei; and that no such connections existed . . . [Full Text of this Article]

Alastair Compston

Cambridge


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