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Brain Advance Access originally published online on March 17, 2009
Brain 2009 132(4):831-832; doi:10.1093/brain/awp051
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© The Author (2009). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Scientific Commentary

Too much of a good thing: increased grey matter in boys with conduct problems and callous-unemotional traits

R. J. R. Blair

Mood and Anxiety Program, Department of Health and Human Services, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. E-mail: jamesblair@mail.nih.gov

The first 10% of the full text of this article appears below.

It is interesting to consider how far the science of a neural substrate for lack of emotion in driving callous behaviour in boys has progressed. Almost 20 years ago, sufficient controversy surrounded holding a conference on the genetics of criminal behaviour that the meeting was moved from the USA to the UK. Now, there is widespread agreement that—in this context—biology cannot be ignored. Fortunately, though, the progress is not just in tolerance for the field, but also in sophistication of the field. It is now relatively uncommon to see references to the biology or genetics of anti-social behaviour. Rather, the emphasis has switched to the biology of specific forms of emotional disruption that give rise to specific forms of anti-social behaviour. There is no biology of criminal behaviour; given sufficient gain and insignificant cost, . . . [Full Text of this Article]


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