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Brain Advance Access published online on October 14, 2008
Brain, doi:10.1093/brain/awn259
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© The Author (2008). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Migraine headache is not associated with cerebral or meningeal vasodilatation—a 3T magnetic resonance angiography study

Antoinette MaassenVanDenBrink1, Dirk Jan Duncker2 and Pramod R. Saxena1

1Erasmus MC - Division of Pharmacology, Vascular and Metabolic Diseases, Department of Internal Medicine and 2Erasmus MC - Department of Experimental Cardiology

Correspondence to: Antoinette MaassenVanDenBrink, Erasmus MC - Division of Pharmacology, Vascular and Metabolic Diseases, Department of Internal Medicine, PO Box 2040, Rotterdam 3000 CA, The Netherlands E-mail: a.vanharen-maassenvandenbrink@erasmusmc.nl

Received July 1, 2008. Accepted September 15, 2008.

The first 10% of the full text of this article appears below.

Sir, with great interest, we read the article by Schoonman et al. (2008), who claim that ‘in contrast to widespread belief, migraine attacks are not associated with vasodilatation of cerebral or meningeal blood vessels’ and, therefore, ‘future anti-migraine agents may not require vasoconstrictor action’. Whereas the methodology used in this investigation is elegant, we disagree with their claim for the following reasons.

First, it may be noted that Schoonman et al. (2008) did observe vasodilatation . . . [Full Text of this Article]


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