Brain, Vol. 123, No. 2, 203-204,
February 2000
© 2000 Oxford University Press
Editorial |
Axonal lesions in multiple sclerosis: an old story revisited
Institute of Neurology, Queen Square, London, UK
The paper by Lovas et al. (2000) published in this issue of Brain is the latest in a series of studies dealing with axonal pathology in multiple sclerosis lesions. The recent re-emergence of interest by researchers in this aspect of multiple sclerosis pathology may at first seem to be at odds with the concept that defines multiple sclerosis as an inflammatory demyelinating disease of the central nervous system with (relatively) spared axons. The recognition that axonal damage occurs in multiple sclerosis lesions is, however, not new, as several of the classical studies documented axonal degeneration, described the presence of Wallerian degeneration and even attempted to quantitate axonal loss.
References
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  J. T. Phillips Rethinking Multiple Sclerosis Arch Neurol, January 1, 2001; 58(1): 30 - 32. [Full Text] [PDF]
|
|
|
|
 |
|
 A. J Thompson Neurological rehabilitation: from mechanisms to management J. Neurol. Neurosurg. Psychiatry, December 1, 2000; 69(6): 718 - 722. [Full Text] [PDF]
|
|