Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (22)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Hallett, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hallett, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Brain, Vol. 123, No. 9, 1765-1766, September 2000
© 2000 Oxford University Press

Editorial

Disorder of movement preparation in dystonia

Mark Hallett, MD

Human Motor Control Section, NINDS, National Institutes of Health Bethesda, MD, USA

Dystonia is undoubtedly characterized by a disorder of movement execution. In many patients, the `involuntary movements' are brought about entirely by attempted voluntary movement. Only in more severe cases are there truly involuntary movements, but even they are exacerbated by volition. The EMG pattern underlying movement demonstrates too much motor activation. There is excessive activation of antagonists, overflow into synergists, unnecessarily activated muscles and prolongation of muscle activation. Such activation gives rise to abnormal muscle spasms and incoordination.

A number of recent studies seem to indicate that excessive muscle activation is due to a deficiency of inhibition (Berardelli et al., 1998Go; Hallett, 1998Go). . . . [Full Text of this Article]

References


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Neurol. Neurosurg. PsychiatryHome page
A Quartarone, F Morgante, A Sant'Angelo, V Rizzo, S Bagnato, C Terranova, H R Siebner, A Berardelli, and P Girlanda
Abnormal plasticity of sensorimotor circuits extends beyond the affected body part in focal dystonia
J. Neurol. Neurosurg. Psychiatry, September 1, 2008; 79(9): 985 - 990.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
C. Dresel, B. Haslinger, F. Castrop, A. M. Wohlschlaeger, and A. O. Ceballos-Baumann
Silent event-related fMRI reveals deficient motor and enhanced somatosensory activation in orofacial dystonia
Brain, January 1, 2006; 129(1): 36 - 46.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
M. Carbon, S. Su, V. Dhawan, D. Raymond, S. Bressman, and D. Eidelberg
Regional metabolism in primary torsion dystonia: Effects of penetrance and genotype
Neurology, April 27, 2004; 62(8): 1384 - 1390.
[Abstract] [Full Text] [PDF]