Brain, Vol. 123, No. 9, 1903-1912,
September 2000
© 2000 Oxford University Press
Functional delineation of the human occipito-temporal areas related to face and scene processing
A PET study
1 Department of Behavioral and Brain Sciences, Primate Research Institute, Kyoto University, Inuyama, 2 Department of Nuclear Medicine and Radiology, IDAC, Tohoku University, Sendai, 3 National Institute for Longevity Sciences, Obu, Japan, 4 C. O. Vogt Institute of Brain Research, University of Düsseldorf, Düsseldorf and 5 Institute of Medicine, Research Center, Julich, Germany
Correspondence to:
Dr Katsuki Nakamura, Department of Behavioral and Brain Sciences, Primate Research Institute, Kyoto University, Kanrin, Inuyama, Aichi 484-8506, Japan E-mail: knakamur{at}pri.kyoto-u.ac.jp
By measuring regional cerebral blood flow using PET, we delineated the roles of the occipito-temporal regions activated by faces and scenes. We asked right-handed normal subjects to perform three tasks using facial images as visual stimuli: in the face familiar/unfamiliar discrimination (FF) task, they discriminated the faces of their friends and associates from unfamiliar ones; in the face direction discrimination (FD) task, they discriminated the direction of each unfamiliar face; in the dot location discrimination (DL) task, they discriminated the location of a red dot on a scrambled face. The activity in each task was compared with that in the control fixation (CF) task, in which they fixated on the centre of a display without visual stimuli. The DL task activated the occipital cortices and posterior fusiform gyri bilaterally. During the FD task, the activation extended anteriorly in the right fusiform gyrus and laterally to the right inferior temporal cortex. The FF task further activated the right temporal pole. To examine whether the activation due to faces was face-specific, we used a scene familiar/unfamiliar discrimination (SF) task, in which the subjects discriminated familiar scenes from unfamiliar ones. Our results suggest that (i) the occipital cortices and posterior fusiform gyri non-selectively respond to faces, scrambled faces and scenes, and are involved mainly in the extraction of physical features of complex visual images; (ii) the right inferior temporal/fusiform gyrus responds selectively to faces but not to non-face stimuli and is involved in the visual processing related to face perception, whereas the bilateral parahippocampal gyri and parieto-occipital junctions respond selectively to scenes and are involved in processing related to scene perception; and (iii) the right temporal pole is activated during the discrimination of familiar faces and scenes from unfamiliar ones, and is probably involved in the recognition of familiar objects.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  L. Garrido, N. Furl, B. Draganski, N. Weiskopf, J. Stevens, G. C.-Y. Tan, J. Driver, R. J. Dolan, and B. Duchaine Voxel-based morphometry reveals reduced grey matter volume in the temporal cortex of developmental prosopagnosics Brain, November 3, 2009; (2009) awp271v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Pourtois, S. Schwartz, M. Spiridon, R. Martuzzi, and P. Vuilleumier Object Representations for Multiple Visual Categories Overlap in Lateral Occipital and Medial Fusiform Cortex Cereb Cortex, August 1, 2009; 19(8): 1806 - 1819. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. K. Simmons, M. Reddish, P. S. F. Bellgowan, and A. Martin The Selectivity and Functional Connectivity of the Anterior Temporal Lobes Cereb Cortex, July 20, 2009; (2009) bhp149v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Rajimehr, J. C. Young, and R. B. H. Tootell An anterior temporal face patch in human cortex, predicted by macaque maps PNAS, February 10, 2009; 106(6): 1995 - 2000. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Tsanov and D. Manahan-Vaughan Synaptic Plasticity from Visual Cortex to Hippocampus: Systems Integration in Spatial Information Processing Neuroscientist, December 1, 2008; 14(6): 584 - 597. [Abstract] [PDF]
|
|
|
|
 |
|
 I. Kahn, J. R. Andrews-Hanna, J. L. Vincent, A. Z. Snyder, and R. L. Buckner Distinct Cortical Anatomy Linked to Subregions of the Medial Temporal Lobe Revealed by Intrinsic Functional Connectivity J Neurophysiol, July 1, 2008; 100(1): 129 - 139. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. R. MICKLEY and E. A. KENSINGER Emotional valence influences the neural correlates associated with remembering and knowing Cogn Affect Behav Neurosci, June 1, 2008; 8(2): 143 - 152. [Abstract] [PDF]
|
|
|
|
|
|
N. Kriegeskorte, E. Formisano, B. Sorger, and R. Goebel Individual faces elicit distinct response patterns in human anterior temporal cortex PNAS, December 18, 2007; 104(51): 20600 - 20605. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Johnson and M. D. Rugg Recollection and the Reinstatement of Encoding-Related Cortical Activity Cereb Cortex, November 1, 2007; 17(11): 2507 - 2515. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. P. MacEvoy and R. A. Epstein Position Selectivity in Scene- and Object-Responsive Occipitotemporal Regions J Neurophysiol, October 1, 2007; 98(4): 2089 - 2098. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. R. Olson, A. Plotzker, and Y. Ezzyat The Enigmatic temporal pole: a review of findings on social and emotional processing Brain, July 1, 2007; 130(7): 1718 - 1731. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. F. Barrett, E. Bliss-Moreau, S. L. Duncan, S. L. Rauch, and C. I. Wright The amygdala and the experience of affect Soc Cogn Affect Neurosci, June 1, 2007; 2(2): 73 - 83. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Skuse Genetic influences on the neural basis of social cognition Phil Trans R Soc B, December 29, 2006; 361(1476): 2129 - 2141. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. E. Doucet, F. Bergeron, M. Lassonde, P. Ferron, and F. Lepore Cross-modal reorganization and speech perception in cochlear implant users Brain, December 1, 2006; 129(12): 3376 - 3383. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Satoh, K. Takeda, K. Nagata, E. Shimosegawa, and S. Kuzuhara Positron-emission tomography of brain regions activated by recognition of familiar music. AJNR Am. J. Neuroradiol., May 1, 2006; 27(5): 1101 - 1106. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Thompson, K. Patterson, and J. R. Hodges Left/right asymmetry of atrophy in semantic dementia: Behavioral-cognitive implications Neurology, November 11, 2003; 61(9): 1196 - 1203. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Sato and K. Nakamura Visual Response Properties of Neurons in the Parahippocampal Cortex of Monkeys J Neurophysiol, August 1, 2003; 90(2): 876 - 886. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R.N. Henson, Y. Goshen-Gottstein, T. Ganel, L.J. Otten, A. Quayle, and M.D. Rugg Electrophysiological and Haemodynamic Correlates of Face Perception, Recognition and Priming Cereb Cortex, July 1, 2003; 13(7): 793 - 805. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Vuilleumier, C. Mohr, N. Valenza, C. Wetzel, and T. Landis Hyperfamiliarity for unknown faces after left lateral temporo-occipital venous infarction: a double dissociation with prosopagnosia Brain, April 1, 2003; 126(4): 889 - 907. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R.N.A. Henson, T. Shallice, M.L. Gorno-Tempini, and R.J. Dolan Face Repetition Effects in Implicit and Explicit Memory Tests as Measured by fMRI Cereb Cortex, February 1, 2002; 12(2): 178 - 186. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. L. Gorno-Tempini and C. J. Price Identification of famous faces and buildings: A functional neuroimaging study of semantically unique items Brain, October 1, 2001; 124(10): 2087 - 2097. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y Wada and T Yamamoto Selective impairment of facial recognition due to a haematoma restricted to the right fusiform and lateral occipital region J. Neurol. Neurosurg. Psychiatry, August 1, 2001; 71(2): 254 - 257. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. J. Shah, J. C. Marshall, O. Zafiris, A. Schwab, K. Zilles, H. J. Markowitsch, and G. R. Fink The neural correlates of person familiarity: A functional magnetic resonance imaging study with clinical implications Brain, April 1, 2001; 124(4): 804 - 815. [Abstract] [Full Text] [PDF]
|
|