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Brain, Vol. 124, No. 7, 1467-1468, July 2001
© 2001 Oxford University Press

Book reviews

MOLECULAR MECHANISMS OF NEURODEGENERATIVE DISEASES.

By Marie-Francoise Chesselet. 2000. Totowa: Humana Press. Price $125.00. Pp. 410. ISBN 0-89603-804-1.

Patrick F. Chinnery

Department of Neurology, University of Newcastle upon Tyne, Newcastle upon Tyne, UK

The development of cellular and animal models of neurodegenerative disease has fuelled research into the basic mechanisms of neurodegeneration over the last decade. The profusion of original papers covering this topic reflects these advances. A Medline search between 1980 and 1990 identified 500 original articles specifically addressing the mechanisms of neurodegeneration, but in a similar time period between 1990 and March 2001, the number increased 10-fold to over 5500. As the editor of Molecular Mechanisms of Neurodegenerative Diseases points out, a comprehensive review of the literature would require much more than the 500 folio pages in this book, so there has to be a compromise. There are two . . . [Full Text of this Article]


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