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Brain, Vol. 124, No. 9, 1880-1881, September 2001
© 2001 Oxford University Press

Book reviews

CENTRAL NERVOUS SYSTEM DISEASES: INNOVATIVE ANIMAL MODELS FROM LAB TO CLINIC

By Dwaine F. Emerich, Reginald L. Dean III and Paul R. Sanberg. 2000. New Jersey: Humana Press. Price US $145. Pp. 528. ISBN 1-89603-724-X.

A. E. Rosser

School of Biosciences, Cardiff University, Cardiff, UK

This book, written and edited by neuroscientists with extensive experience of CNS animal models, provides a critical review of the current status of such models for some of the major CNS diseases. The continued development and analysis of animal models of disease is a crucial part of neuroscience research, and a sound understanding of the subtleties and limitation of these models is key to the proper design and interpretation of experiments in which they are used. For any particular condition, there may be a range of models, some well established and validated over many years and others, such as many of the recently emerging transgenic models, less well . . . [Full Text of this Article]


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