Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (105)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Karnath, H.-O.
Right arrow Articles by Rorden, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Karnath, H.-O.
Right arrow Articles by Rorden, C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Brain, Vol. 125, No. 2, 350-360, February 1, 2002
© 2002 Oxford University Press

The subcortical anatomy of human spatial neglect: putamen, caudate nucleus and pulvinar

Hans-Otto Karnath1, Marc Himmelbach1 and Chris Rorden2

1 Department of Cognitive Neurology, University of Tübingen, Tübingen, Germany and 2 School of Psychology, University of Nottingham, Nottingham, UK

Correspondence to: Hans-Otto Karnath, MD, Department of Cognitive Neurology, University of Tübingen, Hoppe-Seyler-Strasse 3, D-72076 Tübingen, Germany E-mail: Karnath{at}uni-tuebingen.de

Various studies have documented that right hemispheric lesions restricted to the basal ganglia or to the thalamus may evoke spatial neglect. However, for methodological reasons, the exact anatomical correlate of spatial neglect within these two subcortical structures still remained uncertain. The present study identified these locations by comparing the anatomy of subcortical lesions to the basal ganglia or thalamus between neglect and control patients. Analysis revealed that the putamen, the pulvinar and, to a smaller degree, the caudate nucleus are the subcortical structures typically associated with spatial neglect in humans. All these structures have direct anatomical connections to the superior temporal gyrus (STG), which recently has been identified as the neural correlate of spatial neglect in the human cortex. Therefore, it is assumed that the right putamen, caudate nucleus, pulvinar and STG form a coherent corticosubcortical anatomical network in the genesis of spatial neglect in humans.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Cereb CortexHome page
S.L. Fairhall, I. Indovina, J. Driver, and E. Macaluso
The Brain Network Underlying Serial Visual Search: Comparing Overt and Covert Spatial Orienting, for Activations and for Effective Connectivity
Cereb Cortex, December 1, 2009; 19(12): 2946 - 2958.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
H.-O. Karnath, C. Rorden, and L. F. Ticini
Damage to White Matter Fiber Tracts in Acute Spatial Neglect
Cereb Cortex, October 1, 2009; 19(10): 2331 - 2337.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Wilke, K.-M. Mueller, and D. A. Leopold
Neural activity in the visual thalamus reflects perceptual suppression
PNAS, June 9, 2009; 106(23): 9465 - 9470.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
E. C. Petrie, D. J. Cross, D. Galasko, G. D. Schellenberg, M. A. Raskind, E. R. Peskind, and S. Minoshima
Preclinical Evidence of Alzheimer Changes: Convergent Cerebrospinal Fluid Biomarker and Fluorodeoxyglucose Positron Emission Tomography Findings
Arch Neurol, May 1, 2009; 66(5): 632 - 637.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
W. Ilg, M. A. Giese, E. R. Gizewski, B. Schoch, and D. Timmann
The influence of focal cerebellar lesions on the control and adaptation of gait
Brain, November 1, 2008; 131(11): 2913 - 2927.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
P. Bartolomeo, M. Thiebaut de Schotten, and F. Doricchi
Left Unilateral Neglect as a Disconnection Syndrome
Cereb Cortex, November 1, 2007; 17(11): 2479 - 2490.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
P. L. Cotton and A. T. Smith
Contralateral Visual Hemifield Representations in the Human Pulvinar Nucleus
J Neurophysiol, September 1, 2007; 98(3): 1600 - 1609.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. Sapir, J. B. Kaplan, B. J. He, and M. Corbetta
Anatomical Correlates of Directional Hypokinesia in Patients with Hemispatial Neglect
J. Neurosci., April 11, 2007; 27(15): 4045 - 4051.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. J. Geng, E. Eger, C. C. Ruff, A. Kristjansson, P. Rotshtein, and J. Driver
On-Line Attentional Selection From Competing Stimuli in Opposite Visual Fields: Effects on Human Visual Cortex and Control Processes
J Neurophysiol, November 1, 2006; 96(5): 2601 - 2612.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
O. C. Singer, M. C. Humpich, H. Laufs, H. Lanfermann, H. Steinmetz, and T. Neumann-Haefelin
Conjugate Eye Deviation in Acute Stroke: Incidence, Hemispheric Asymmetry, and Lesion Pattern
Stroke, November 1, 2006; 37(11): 2726 - 2732.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
K. Finke, P. Bublak, M. Dose, H. J. Muller, and W. X. Schneider
Parameter-based assessment of spatial and non-spatial attentional deficits in Huntington's disease
Brain, May 1, 2006; 129(5): 1137 - 1151.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
K. C. Park, B. H. Lee, E. J. Kim, M. H. Shin, K. M. Choi, S. S. Yoon, S. U. Kwon, C. S. Chung, K. H. Lee, K. M. Heilman, et al.
Deafferentation-disconnection neglect induced by posterior cerebral artery infarction
Neurology, January 10, 2006; 66(1): 56 - 61.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
H.-O. Karnath, R. Zopf, L. Johannsen, M. F. Berger, T. Nagele, and U. Klose
Normalized perfusion MRI to identify common areas of dysfunction: patients with basal ganglia neglect
Brain, October 1, 2005; 128(10): 2462 - 2469.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. M. Palva, S. Palva, and K. Kaila
Phase Synchrony among Neuronal Oscillations in the Human Cortex
J. Neurosci., April 13, 2005; 25(15): 3962 - 3972.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
H.-O. Karnath, L. Johannsen, D. Broetz, and W. Kuker
Posterior thalamic hemorrhage induces "pusher syndrome"
Neurology, March 22, 2005; 64(6): 1014 - 1019.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
A Farne, L J Buxbaum, M Ferraro, F Frassinetti, J Whyte, T Veramonti, V Angeli, H B Coslett, and E Ladavas
Patterns of spontaneous recovery of neglect and associated disorders in acute right brain-damaged patients
J. Neurol. Neurosurg. Psychiatry, October 1, 2004; 75(10): 1401 - 1410.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
H.-O. Karnath, M. Fruhmann Berger, W. Kuker, and C. Rorden
The Anatomy of Spatial Neglect based on Voxelwise Statistical Analysis: A Study of 140 Patients
Cereb Cortex, October 1, 2004; 14(10): 1164 - 1172.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
L. Pessoa and L. G. Ungerleider
Neural Correlates of Change Detection and Change Blindness in a Working Memory Task
Cereb Cortex, May 1, 2004; 14(5): 511 - 520.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
H.-O. Karnath, M. Fruhmann Berger, R. Zopf, and W. Kuker
Using SPM normalization for lesion analysis in spatial neglect
Brain, April 1, 2004; 127(4): E10 - E10.
[Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
A Parton, P Malhotra, and M Husain
Hemispatial neglect
J. Neurol. Neurosurg. Psychiatry, January 1, 2004; 75(1): 13 - 21.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. Kastner, D. H. O'Connor, M. M. Fukui, H. M. Fehd, U. Herwig, and M. A. Pinsk
Functional Imaging of the Human Lateral Geniculate Nucleus and Pulvinar
J Neurophysiol, January 1, 2004; 91(1): 438 - 448.
[Abstract] [Full Text]

Home page
 BrainHome page
N. Kapur, P. Abbott, A. Lowman, and R. G. Will
The neuropsychological profile associated with variant Creutzfeldt-Jakob disease
Brain, December 1, 2003; 126(12): 2693 - 2702.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
A. E. Hillis, R. J. Wityk, P. B. Barker, J. A. Ulatowski, and M. A. Jacobs
Change in Perfusion in Acute Nondominant Hemisphere Stroke May Be Better Estimated by Tests of Hemispatial Neglect Than by the National Institutes of Health Stroke Scale
Stroke, October 1, 2003; 34(10): 2392 - 2396.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
D. J. Mort, P. Malhotra, S. K. Mannan, C. Rorden, A. Pambakian, C. Kennard, and M. Husain
The anatomy of visual neglect
Brain, September 1, 2003; 126(9): 1986 - 1997.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
J. D. Schmahmann
Vascular Syndromes of the Thalamus
Stroke, September 1, 2003; 34(9): 2264 - 2278.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
A. R. Riestra, K. B. Womack, G. P. Crucian, and K. M. Heilman
Is the middle between both halves?: Midpoint location and segment size estimation in neglect
Neurology, November 26, 2002; 59(10): 1580 - 1584.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.