Brain, Vol. 126, No. 4, 1009-1011,
April 2003
© 2003 Guarantors of Brain
doi: 10.1093/brain/awg078
Book Review |
DEGENERATION AND REGENERATION IN THE NERVOUS SYSTEM
Department of Neuropathology, Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK
DEGENERATION AND REGENERATION IN THE NERVOUS SYSTEM
Edited by Norman R. Saunders and Katarzyna M. Dziegielewska
2000. Amsterdam: Harwood Academic Publishers
Price £39. pp. 348. ISBN 90-5823-022-8.
| The first 150 words of the full text of this article appear below. |
Repair of the damaged human central nervous system (CNS) remains a much sought after but still elusive goal of patients, clinicians and scientists. As noted by Douglas Brown, in the opening chapter of this book, patients and their families have been alternately excited by the prospect of cure and frustrated by the delays in achieving this. Clinicians have found themselves in an awkward position trying to bridge the gap between the expectations of patients, the enthusiasm of researchers, and the limitations of available treatment. This book comprises 14 reviews of different aspects of degeneration, regeneration and adaptation to injury in the nervous system, with an emphasis on interventions that promote the regrowth of damaged axons. Most of the reviews relate to degeneration and regeneration in the CNS but three of the chapters focus on the peripheral nervous system.
In the first chapter, Brown analyses the findings in several studies of