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Brain, Vol. 126, No. 5, 1013-1014, May 2003
© 2003 Guarantors of Brain
doi: 10.1093/brain/awg141

Editorial

Pneumococcal meningitis: antibiotics essential but insufficient

Larry E. Davis1 and John E. Greenlee2

1 Neurology Service, New Mexico VA Health Care System, Albuquerque, NM, USA 2 Neurology Service, Salt Lake Veterans Affairs Medical Center and Department of Neurology, University of Utah School of Medicine, Salt Lake City, UT, USA

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Prior to the discovery of antibiotics, bacterial meningitis was almost invariably fatal: over 95% of individuals developing bacterial meningitis died, and the few individuals surviving infection were neurologically devastated. With the advent of antibiotics, bacterial meningitis became a treatable condition, and the primary objective in the patient with bacterial meningitis became, appropriately, prompt diagnosis and initiation of antibiotic therapy.

Until the latter part of the twentieth century, bacterial meningitis was predominantly a condition of infancy and early childhood, caused in large part by Haemophilus influenzae type B. Streptococcus pneumoniae, although the most common cause of meningitis in adults, received . . . [Full Text of this Article]


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