Brain, Vol. 127, No. 1, 231-233, 2004
© 2004 Guarantors of Brain
doi: 10.1093/brain/awh010
Book Review |
MILD COGNITIVE IMPAIRMENT: AGING TO ALZHEIMERS DISEASE
MILD COGNITIVE IMPAIRMENT: AGING TO ALZHEIMERS DISEASEEdited by Ronald C. Petersen
2003. Oxford: Oxford University Press
Price: £39.50. ISBN 0-19-512342-5.
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This is an interesting, thought-provoking, sometimes controversial and eminently readable book. Mild cognitive impairment (MCI) refers to the borderland between normal ageing and dementia. The term MCI has recent origins, having been introduced only in the last decade in recognition of the fact that the onset of dementia is insidious. There is a prodromal phase during which an individual functions at a lower level than normal, yet the changes in cognition are insufficient to warrant a classification of dementia. Herein lies a fundamental conceptual difference between MCI and descriptive labels that acquired prominence in earlier decades, such as benign senescent forgetfulness and age-associated memory impairment. These latter terms implied changes in memory, which were thought to be largely consistent with and the product of normal ageing. MCI, by contrast, is construed as abnormal
Cerebral Function UnitGreater Manchester Neuroscience CentreHope HospitalSalford, UK