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Brain 2004 127(11):E18; doi:10.1093/brain/awh279
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Brain Vol. 127 No. 11 © Guarantors of Brain 2004; all rights reserved

Letter to the Editor

Conceptual divide between adaptive and pathogenetic phenomena in migraine: nausea and vomiting

Vinod K. Gupta

Dubai Police Medical Services, Medical, Dubai, United Arab Emirates

Correspondence to: Vinod K. Gupta, Dubai Police Medical Services, Medical, Dubai, United Arab Emirates E-mail: docgupta@emirates.net.ae

Received April 18, 2004. Accepted June 18, 2004.

The first 10% of the full text of this article appears below.

Drummond and Granston (2004)Go believe that nausea and headache, two key symptoms of migraine, interact pathogenetically by reinforcing each other in a vicious circle during attacks. These authors elaborate upon the role of extracranial vasodilatation during optokinetic stimulation—painful as well as painless—in patients with migraine and control subjects, respectively, as an important component of the defence (flight-or-fight) response. In considering the pathogenetic role in migraine of extracranial neurovascular responses to stress, it bears emphasis that extracranial vasoconstriction—as seen in conjunctival vessels—is as . . . [Full Text of this Article]


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