Brain, Vol. 127, No. 5, 1211-1212, 2004
© 2004 Guarantors of Brain
doi: 10.1093/brain/awh056
Book Review |
THE PARAHIPPOCAMPAL REGION: ORGANIZATION AND ROLE IN COGNITIVE FUNCTION
THE PARAHIPPOCAMPAL REGION: ORGANIZATION AND ROLE IN COGNITIVE FUNCTIONBy Menno Witter and Floris Wouterlood
2002. Oxford: Oxford University Press
Price £69.50. ISBN 0198509170.
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In 1953 the patient known by his initials as H.M. underwent surgery to have tissue removed from his medial temporal lobes for the purposes of controlling intractable epilepsy. Upon awakening from the procedure he was found to have acquired a profound anterograde (and temporally graded retrograde) amnesia. This event triggered an eruption of research activity aimed at determining which particular temporal lobe structures were critically involved in the memory dysfunction. By the 1970s and early 1980s it began to look as though the hippocampus and perhaps the amygdala were responsible for the acquisition of consciously accessible, declarative memory and that damage to these structures alone was sufficient to produce the amnesic syndrome. As a result, the
Department of Psychology, University of Otago, Otago, New Zealand