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Letter to the Editor |
Mitochondrial changes in skeletal muscle in amyotrophic lateral sclerosis and other neurogenic atrophiesa comment
Departments of 1 Epileptology and 2 Neurology, University of Bonn, Bonn and 3 Department of Neurology II, University of Magdeburg, Magdeburg, Germany
Correspondence to: Wolfram S. Kunz, PhD, University of Bonn, Department of Epileptology, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany E-mail: wolfram.kunz@ukb.uni-bonn.de
Received July 15, 2005. Accepted September 9, 2005.
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Sir,
We read with great interest the article by Krasnianski et al. (2005)
recently published in your journal. The authors report the absence of specific alterations of respiratory chain activities in skeletal muscle of patients with amyotrophic lateral sclerosis (ALS) and neurogenic atrophies (NA). While the data concerning NA patients are completely in line with our previous observations on six patients with spinal muscular atrophy and two patients with TaySachs syndrome (cf. Vielhaber et al.,
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A. Krasnianski, M. Deschauer, M. Krasnianski, and S. Zierz Reply to 'Mitochondrial changes in skeletal muscle in amyotrophic lateral sclerosis and other neurogenic atrophies--a comment'. Brain, March 1, 2006; 129(Pt 3): E41 - E41. [Full Text] [PDF] |
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