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Letter to the Editor |
Time-resolved sex differences in language lateralization
Functional Brain Mapping Laboratory, Department of Neurology, University Hospital and Department of Fundamental Neuroscience, University Medical School, Geneva, Switzerland
Correspondence to: Christoph M. Michel, Functional Brain Mapping Laboratory, Neurology Clinic, University Hospital, 1211 Geneva, Switzerland E-mail: christoph.michel@medecine.unige.ch
| The first 150 words of the full text of this article appear below. |
Many clinical, behavioural and brain imaging studies have suggested that language functions are less asymmetrical in women than in men. Sommer and colleagues challenge this view in a recent review on the outcome of 24 functional brain imaging studies (PET, functional MRI or functional transcranial Doppler ultrasound) that looked at possible sex differences in language lateralization. A vote count analysis over all studies revealed a much higher score for those studies that reported no sex differences. In addition, a meta-analysis of the lateralization index in 13 of these studies revealed no statistically significant difference between men and women. The authors concluded that the hypothesis of sex differences in cortical language representation probably has to be rejected at the population level (Sommer et al., 2004
). We believe that the hypothesis of subtle, but crucial sex differences in language representation should not be rejected on these grounds, considering the selective
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