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Age at disability milestones in multiple sclerosis and history of multiple sclerosis: a unifying concept
Department of Neurology, University of California San Francisco, USA
Correspondence to: Dr Douglas Goodin, Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, Room M794, 350 Parnassus Avenue, Suite 908, San Francisco, CA 94705-0114, USA E-mail: douglas.goodin@ucsf.edu
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On the basis of a reanalysis of the French natural history cohort of multiple sclerosis (MS) patients (Confavreux and Vukusic, 2006a
, b
), Confavreux and Vukusic put forth a unifying hypotheses that the emergence of the progressive phase of [MS] might just be an effect of age, rather than the effect of a change in the pathogeny of