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The pedunculopontine and peripeduncular nuclei: a tale of two structures
1Unit of Functional Neurosurgery, Institute of Neurology & National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, 2Department of Neurosurgery, Essex Centre for Neurosciences, Queen's Hospital, Romford, Essex, RM7 0AG, UK, 3Department of Anatomy, Genetics & Cellular Biology, University of Malta, Msida, MSD.06, Malta and 4Department of Neurosurgery, University Hospital, Umeå, Sweden
Correspondence to: Ludvic Zrinzo E-mail: luz@dr.com
Received February 15, 2007. Accepted March 15, 2007.
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Research on the pedunculopontine nucleus (PPN) has identified this structure as a potential new target for deep brain stimulation (DBS) in patients with axial movement disorders refractory to other forms of treatment (Pahapill and Lozano, 2000
; Jenkinson et al., 2004). Stefani et al. recently presented their surgical approach for DBS of the PPN (Stefani et al.,
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