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Brain Advance Access originally published online on June 16, 2008
Brain 2008 131(7):1684-1685; doi:10.1093/brain/awn131
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© The Author (2008). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Scientific Commentary

‘Seronegative’ myasthenia gravis is no longer seronegative

The first 10% of the full text of this article appears below.

High-affinity IgG autoantibodies to muscle nicotinic acetylcholine receptors (AChRs) were discovered to cause myasthenia gravis (MG) and its animal model more than 30 years ago (Patrick and Lindstrom, 1973Go; Lindstrom et al., 1976aGo, b; Vincent et al., 2006Go), and the antigenic structure of muscle AChRs is still being actively investigated (Kalamida et al., 2007Go; Lindstrom et al., 2008Go). Immune precipitation of AChRs tagged in their . . . [Full Text of this Article]

Jon Lindstrom

Department of Neuroscience, Medical School of the University of Pennsylvania, Pennsylvania, PA, USA

E-mail: jslkk@mail.med.upenn.edu


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