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Brain Advance Access published online on July 25, 2008

Brain, doi:10.1093/brain/awn158
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Cortical maps and modern phrenology

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Cortical cytoarchitectonics has had a chequered history. Beginning with Meynert's discovery of the systematic layering of neurons in the cerebral cortex and with Betz's discovery of the giant cells that bear his name, and initially influenced by phrenological ideas, over the years it has gone in and out of favour as conceptual fashions and methods of investigation have changed. Currently, it seems to be enjoying resurgent popularity as modern phrenologists, equipped with the powerful tools of functional MRI, seek to relate tiny pseudo-coloured patches of slightly enhanced cortical activity associated with some limited cognitive function to an underlying structural correlate. The reappearance, therefore, of what was once a classical atlas of human cortical architectonics can be seen as a landmark, especially when accompanied by an insightful survey of the history of the field and its relevance to efforts at localizing function in the human cortex using modern imaging techniques.

Die . . . [Full Text of this Article]

Edward G. Jones

Center for Neuroscience
University of California, Davis


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