About the Cover
Cover design PET using the GABAA ligand [11C]flumazenil revealed significantly decreased relative binding in motor and extra-motor cortex in subjects with amyotrophic lateral sclerosis (ALS) compared with normal controls. This probably reflects loss of both pyramidal and inter-neurones and provides a new approach to quantifying the cerebral lesion in ALS. From `Extramotor involvement in ALS: PET studies with the GABAA ligand [11C]flumazenil' by C. M. Lloyd et al., 22892296.
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