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Cover design In situ hybridization histochemistry for neuropeptide Y mRNA and somatostatin mRNA in the hilar region of tissue from patients with temporal lobe epilepsy. Detection of 35S-labelled oligonucleotide probes for neuropeptide Y and somatostatin on emulsion-dipped preparations counterstained with toluidine blue. Upper panel: distribution of neuropeptide Y mRNA-synthesizing neurones within the dentate hilus. Middle panel: higher magnification showing the clear intrahilar ditribution of of neuropeptide Y mRNA-synthesizing neurones. Lower panel: higher magnification still showing labelling pattern for somatostatin mRNA-positive hilar cells. From `Somatostatin- and neuropeptide Y-synthesizing neurones in the fascia dentata of humans with temporal lobe epilepsy' by L.E.Sundstrom et al., 688697.
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